Nuclear Magnetic Resonance
The Nuclear Magnetic Resonance (NMR) platform provides atomic level information about molecules. The expert team can accommodate external work, including work as a package with metabolomics such as mass spectrometry or high-resolution mass spectrometry.
The platform has two solution-state instruments and our experts can help you decide which is best suited to your project. Both instruments are highly automated being configured with autosamplers and supported by advanced software packages, providing comprehensive characterisation of the systems under investigation.
The team offers a full range of solution NMR experiments on a Bruker Avance Neo 600 instrument equipped with a triple resonance cryoprobe.
The platform offers the ability to identify and quantify synthetic compounds and natural products, small molecule pharmaceuticals and fine chemicals, polymers and biomolecules (such as proteins and polysaccharides) and more.
The platform is able to detect a range of elements qualitatively and quantitatively to help you and identify and measure your molecule of interest through the following methods:
- 1D experiments for 1H, 13C, 19F, 31P • 2D experiments (COSY, HSQC, HMBC, H2BC, NOESY/ROESY, TOCSY)
- 1D quantitative NMR (qNMR)
The expert team can help you make sense of the NMR data to identify your molecule of interest in the following ways:
- Data interpretation
- Written reports
- Combined accurate MS and NMR services
The platform has two solution-state instruments that are highly automated and supported by advanced software packages, providing comprehensive characterisation of synthetic and natural compounds.
In collaboration with the Metabolomics and Proteomics platforms, the platform can also:
- Monitor chemical and enzymatic reactions
- Determine sample concentrations
- Observe molecular interactions
- Collect data for NMR metabolomics analysis
Prices vary according to the type of experiments and sample quantities involved, contact the team for a bespoke quote for your project.