Martin Howard publications

69. M. Guzzo, S. Murray, E. Martineau, S. Lhospice, G. Baronian, L. My, Y. Zhang, L. Espinosa, R. Vincentelli, B. Bratton, J. Shaevitz, V. Molle, M. Howard and T. Mignot:
A gated relaxation oscillator mediated by FrzX controls morphogenetic movements in Myxococcus xanthus
Nature Microbiol. 3 948–959 (2018)

68. J. Hepworth, R. Antoniou-Kourounioti, R. Bloomer, C. Selga, K. Berggren, D. Cox, B. Collier Harris, J. Irwin, S. Holm, T. Säll, M. Howard and C. Dean:
Absence of warmth permits epigenetic memory of winter in Arabidopsis
Nature Commun. 9 639 (2018)

67. S. Berry, S. Rosa, M. Howard, M. Bühler and C. Dean:
Disruption of an RNA-binding hinge region abolishes LHP1-mediated epigenetic repression
Genes and Dev. 31 2115-2120 (2017)

66. G. Facchetti, F. Chang and M. Howard:
Controlling cell size through sizer mechanisms
Curr. Opin. Sys. Biol. 5 86-92 (2017)

65. H. Yang, S. Berry, T. Olsson, M. Hartley, M. Howard and C. Dean:
Distinct phases of Polycomb silencing to hold epigenetic memory of cold in Arabidopsis
Science 357 1142-1145 (2017)

64. R. Ietswaart, S. Rosa, Z. Wu, C. Dean and M. Howard:
Cell-Size-Dependent Transcription of FLC and Its Antisense Long Non-coding RNA COOLAIR Explain Cell-to-Cell Expression Variation
Cell Systems 4 622-635 (2017) - pdf file 

63. S. Berry, C. Dean and M. Howard:
Slow chromatin dynamics allow Polycomb target genes to filter fluctuations in transcription factor activity
Cell Systems 4 445–457 (2017) - pdf file 
Reviewed in Cell Systems Preview: "Reconciling Epigenetic Memory and Transcriptional Responsiveness"

62. R. Antoniou-Kourounioti and M. Howard:
Quantitative environmentally triggered switching between stable epigenetic states
Chap. 8 p. 169-187 in "Epigenetics and Systems Biology" (2017), ed. L. Ringrose

61. L. Ringrose and M. Howard:
Dissecting chromatin-mediated gene regulation and epigenetic memory through mathematical modelling
Curr. Opin. Sys. Biol. 3 7-14 (2017)

60. H. Yang, M. Howard and C. Dean:
Physical coupling of activation and derepression activities to maintain an active transcriptional state at FLC
Proc. Natl. Acad. Sci. 113 9369-9374 (2016)

59. Z. Wu, R. Ietswaart, F. Liu, H. Yang, M. Howard and C. Dean:
Quantitative regulation of FLC via coordinated transcriptional initiation and elongation
Proc. Natl. Acad. Sci. 113 218-223 (2016)

58. S. Berry, M. Hartley, T. Olsson, C. Dean and M. Howard:
Local chromatin environment of a Polycomb target gene instructs its own epigenetic inheritance
eLife 4 e07205 (2015) - pdf file

57. A. Angel, J. Song, H. Yang, J. Questa, C. Dean and M. Howard:
Vernalizing cold is registered digitally at FLC
Proc. Natl. Acad. Sci. 112 4146-4151 (2015)

56. A. Scialdone and M. Howard:
How plants manage food reserves at night: quantitative models and open questions
Front. Plant Sci. 6 204 (2015) - pdf file

55. R. Ietswaart, F. Szardenings, K. Gerdes and M. Howard:
Competing ParA Structures Space Bacterial Plasmids Equally over the Nucleoid
PLoS Comput. Biol. 10 e1004009 (2014) - pdf file , Supporting information pdf file

54. H. Yang, M. Howard and C. Dean:
Antagonistic Roles for H3K36me3 and H3K27me3 in the Cold-Induced Epigenetic Switch at Arabidopsis FLC
Curr. Biol. 24 1793-1797 (2014) - pdf file

53. K. Pan, T. Saunders, I. Flor-Parra, M. Howard and F. Chang:
Cortical regulation of cell size by a sizer cdr2p
eLife 3 e02040 (2014) - pdf file

52. S. Murray, G. Panis, C. Fumeaux, P. Viollier and M. Howard:
Computational and Genetic Reduction of a Cell Cycle to Its Simplest, Primordial Components
PLoS Biology 11 e1001749 (2013) - pdf file Supporting information pdf file
Reviewed in PLoS Biology synopsis: "Notes from the Cell Cycle World: Less Is More"

51. A. Scialdone, S. Mugford, D. Feike, A. Skeffington, P. Borrill, A. Graf, A. Smith and M. Howard:
Arabidopsis plants perform arithmetic division to prevent starvation at night
eLife 2 e00669 (2013) - pdf file

50. D. Richards, S. Berry and M. Howard:
Illustrations of Mathematical Modeling in Biology: Epigenetics, Meiosis, and an Outlook
Cold Spring Harb. Symp. Quant. Biol. 77 175-181 (2012) - pdf file

49. D. Richards, E. Greer, A. Martin, G. Moore, P. Shaw and M. Howard:
Quantitative Dynamics of Telomere Bouquet Formation
PLoS Comput. Biol. 8 e1002812 (2012) - pdf file , Supporting information pdf file

48. K. Flardh, D. Richards, A. Hempel, M. Howard and M. Buttner:
Regulation of apical growth and hyphal branching in Streptomyces
Curr. Opin. Microbiol. 15 737-743 (2012) - pdf file

47. J. Song, A. Angel, M. Howard and C. Dean:
Vernalization – a cold-induced epigenetic switch
J. Cell Sci. 125 3723-3731 (2012) - pdf file

46. M. Howard:
How to build a robust intracellular concentration gradient
Trends Cell Biol. 22 311-317 (2012) - pdf file
From the cover...

45. D. Richards, A. Hempel, K. Flardh, M. Buttner and M. Howard:
Mechanistic basis of branch-site selection in filamentous bacteria
PLoS Comput. Biol. 8 e1002423 (2012) - pdf file , Supporting information pdf file

44. T. Saunders, K. Pan, A. Angel, Y. Guan, J. Shah, M. Howard and F. Chang:
Noise Reduction in the Intracellular Pom1p Gradient by a Dynamic Clustering Mechanism
Dev. Cell 22 558-572 (2012) - pdf file, Supplemental information pdf file
Reviewed in Nature Rev. Genet. research highlight: "Development: Robust but responsive protein gradients"

43. A. Angel, J. Song, C. Dean and M. Howard:
A Polycomb-based switch underlying quantitative epigenetic memory
Nature 476 105-108 (2011) - pdf file, Supplementary information pdf file
Deutsche Welle news agencyFaculty of 1000

42. M. Howard and K. Gerdes:
What is the mechanism of ParA-mediated DNA movement?
Mol. Microbiol. 78 9-12 (2010) - pdf file

41. F. He, T. Saunders, Y. Wen, D. Cheung, R. Jiao, P.R. ten Wolde, M. Howard and J. Ma:
Shaping a morphogen gradient for positional precision
Biophys. J. 99 697-707 (2010)
pdf file, Supporting Material pdf file

40. K. Gerdes, M. Howard and F. Szardenings:
Pushing and pulling in prokaryotic DNA segregation
Cell 141 927-942 (2010) - pdf file

39. T. Erdmann, M. Howard and P.R. ten Wolde:
Role of spatial averaging in the precision of gene expression patterns
Phys. Rev. Lett. 103 258101 (2009) - pdf file

38. T. Saunders and M. Howard:
When it pays to rush: interpreting morphogen gradients prior to steady-state
Phys. Biol. 6 046020 (2009) - pdf file
Selected as a Highlight of 2009 by Physical Biology

37. S. Ringgaard, J. van Zon, M. Howard and K. Gerdes:
Movement and equipositioning of plasmids by ParA filament disassembly
Proc. Natl. Acad. Sci. 106 19369-19374 (2009) - pdf file , Supporting information pdf file
Recommended by Faculty of 1000

36. T. Saunders and M. Howard:
Morphogen profiles can be optimized to buffer against noise
Phys. Rev. E 80 041902 (2009) - pdf file 
Recommended by Faculty of 1000

35. J. van Zon, G. Tzircotis, E. Caron and M. Howard:
A mechanical bottleneck explains the variation in cup growth during FcγR phagocytosis
Mol. Syst. Biol. 5 298 (2009) - pdf file , Supporting Information pdf file

34. M. Howard:
Cell Division: Experiments and Modelling Unite to Resolve the Middle
Curr. Biol. 19 R67-R69 (2009) - pdf file

33. F. Tostevin and M. Howard:
Modeling the establishment of PAR protein polarity in the one-cell C. elegans embryo
Biophys. J. 95 4512-4522 (2008) - pdf file , Supporting Information pdf file 

32. F. Tostevin, P.R. ten Wolde and M. Howard:
Fundamental limits to position determination by concentration gradients
PLoS Comput. Biol. 3 e78 (2007) - pdf file 

31. K. Kruse, M. Howard and W. Margolin:
An experimentalist's guide to computational modelling of the Min system
Mol. Microbiol. 63 1279-1284 (2007) - pdf file 

30. N. Padte, S. Martin, M. Howard and F. Chang:
The cell-end factor Pom1p inhibits Mid1p in specification of the cell division plane in fission yeast
Curr. Biol. 16 2480-2487 (2006)
pdf file Supporting Information pdf file 
Reviewed in J. Cell Biol. research roundup: "Pom1p Prevents a Spreading Middle"
Reviewed in Curr. Biol. dispatch: "Cell Division: Mid-Level Management"

29. R. Sear and M. Howard:
Modeling dual pathways for the metazoan spindle assembly checkpoint
Proc. Natl. Acad. Sci. 103 16758-16763 (2006) - pdf file 

28. M. Howard:
Cell signalling: changing shape changes the signal
Curr. Biol. 16 R673-R675 (2006) - pdf file

27. F. Tostevin and M. Howard:
A stochastic model of Min oscillations in Escherichia coli and Min protein segregation during cell division
Phys. Biol. 3 1-12 (2006) - pdf file 
Selected as a Highlight of 2006 by Physical Biology

26. M. Howard and P.R. ten Wolde:
Finding the center reliably: robust patterns of developmental gene expression
Phys. Rev. Lett. 95 208103 (2005) - pdf file 

25. K. Doubrovinski and M. Howard:
Stochastic model for Soj relocation dynamics in Bacillus subtilis
Proc. Natl. Acad. Sci. 102 9808-9813 (2005) - pdf file , Supporting information pdf file 

24. U. Täuber, M. Howard and B. Vollmayr-Lee:
Applications of field-theoretic renormalization group methods to reaction-diffusion problems
J. Phys. A 38 R79-R131 (2005) - pdf file

23. M. Howard and K. Kruse:
Cellular organization by self-organization: mechanisms and models for Min protein dynamics
J. Cell Biol. 168 533-536 (2005) - pdf file 

22. C. Baggio, M. Howard and W. van Saarloos:
Dynamics and stability of vortex-antivortex fronts in type II superconductors
Phys. Rev. E. 70 026209 (2004) - pdf file

21. M. Howard:
A mechanism for polar protein localization in bacteria
J. Mol. Biol. 335 655-663 (2004) - pdf file

20. M. Howard and M. van Hecke:
Hole-defect chaos in the one-dimensional complex Ginzburg-Landau equation
Phys. Rev. E. 68 026213 (2003) - pdf file

19. M. Howard and A. Rutenberg:
Pattern formation inside bacteria: fluctuations due to the low copy number of proteins
Phys. Rev. Lett. 90 128102 (2003) - pdf file

18. M. Howard, A. Rutenberg and S. de Vet:
Dynamic compartmentalization of bacteria: accurate division in E. coli
Phys. Rev. Lett. 87 278102 (2001) - pdf file 
Reviewed at Nature news: "Sloshing proteins help bacteria find their waists"

17. M. van Hecke and M. Howard:
Ordered and self-disordered dynamics of holes and defects in the one-dimensional complex Ginzburg-Landau equation
Phys. Rev. Lett. 86 2018-2021 (2001) - pdf file 

16. D. Vernon and M. Howard:
Branching and annihilating Lévy flights
Phys. Rev. E 63 0411161-0411168 (2001) - pdf file

15. P. Fröjdh, M. Howard and K. Lauritsen:
Directed percolation and other systems with absorbing states: impact of boundaries
Int. J. Mod. Phys. B 15 1761-1797 (2001) - pdf file

14. M. Howard and R. Zia:
Fluctuations and correlations in population models with age structure
Int. J. Mod. Phys. B 15 391-402 (2001) - pdf file

13. M. Howard, P. Fröjdh and K. Lauritsen:
Surface critical behavior in systems with nonequilibrium phase transitions
Phys. Rev. E 61 167-183 (2000) - pdf file

12. Y. Goldschmidt, H. Hinrichsen, M. Howard and U. Täuber:
Nonequilibrium critical behavior in unidirectionally coupled stochastic processes
Phys. Rev. E 59 6381-6408 (1999 - pdf file

11. H. Hinrichsen and M. Howard:
A model for anomalous directed percolation
Eur. Phys. J. B 7 635-643 (1999 - pdf file

10. U. Täuber, M. Howard and H. Hinrichsen:
Phys. Rev. Lett. 81 2179 (1998) - pdf file 

9. K. Lauritsen, P. Fröjdh and M. Howard:
Surface critical behavior in systems with absorbing states
Phys. Rev. Lett. 81 2104-2107 (1998) - pdf file

8. M. Howard and C. Godrèche:
Persistence in the voter model: continuum reaction-diffusion approach
J. Phys. A 31 L209-L215 (1998) - pdf file

7. U. Täuber, M. Howard and H. Hinrichsen:
Multicritical behavior in coupled directed percolation processes
Phys. Rev. Lett. 80 2165-2168 (1998) - pdf file

6. P. Fröjdh, M. Howard and K. Lauritsen:
Directed percolation with a wall or edge
J. Phys. A 31 2311-2320 (1998) pdf file

5. M. Howard and U. Täuber:
"Real" versus "imaginary" noise in diffusion limited reactions
J. Phys. A 30 7721-7731 (1997) - pdf file

4. M. Howard and G. Barkema:
Shear flows and segregation in the reaction A+B→Ø
Phys. Rev. E 53 5949-5956 (1996) - pdf file

3. M. Howard:
Fluctuation kinetics in a multispecies reaction-diffusion system
J. Phys. A 29 3437-3460 (1996) - pdf file

2. G. Barkema, M. Howard and J. Cardy:
The reaction-diffusion front for A+B→Ø in one dimension
Phys. Rev. E 53 R2017-R2020 (1996) - pdf file

1. M. Howard and J. Cardy:
Fluctuation effects and multiscaling of the reaction-diffusion front for A+B→Ø
J. Phys. A 28 3599-3621 (1995) - pdf file

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