Bacteria branch out
Streptomyces produce the majority of clinically useful antibiotics, yet we don’t fully understand how they grow
Read the storyStreptomyces produce the majority of clinically useful antibiotics, yet we don’t fully understand how they grow
Read the storyScientists have worked out the structure of a class of enzyme that has been genetically validated as a new drug target in Mycobacterium tuberculosis, a pathogenic bacterium which is responsible for 2 million tuberculosis deaths worldwide each year
Read the storyA novel way of increasing the amounts of antibiotics produced by bacteria has been discovered that could markedly improve the yields of these important compounds in commercial production
Read the storyWorking out the structure of a complex formed when a protein binds to DNA has proved to be key in understanding how an antibiotic-producing organism controls resistance to its own antibiotic, and may be an example of how other antibiotic producers regulate export to prevent self-toxicity
Read the storyTo help in the search for new antibiotics, Juan Pablo Gomez-Escribano and Professor Mervyn Bibb have adapted a strain of Streptomyces coelicolor to express clusters of genes found from genome sequencing projects whose functions are unknown
Read the storyResearchers from the John Innes Centre and the University of East Anglia have recently elucidated the structure and function of an enzyme which is involved in decorating antibiotics with sugar molecules
Read the storyA DNA-based therapy could slash the development time of new drugs to combat antibiotic resistant superbugs
Read the storyAntibiotic resistance is a major problem worldwide and there is an urgent need for new antibiotics to be developed
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