John Innes Centre

Prof Martin Howard

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Curriculum Vitae

  • 1990-1993 BA Physics (1st class) Merton College, Oxford University
  • 1993-1996 D. Phil Theoretical Physics, Oxford University
  • 1996-1998 Postdoctoral Fellow, Niels Bohr Institute, Copenhagen, Denmark
  • 1998-1999 Postdoctoral Fellow, Virginia Tech, Blacksburg, USA
  • 1999-2001 Postdoctoral Fellow, Simon Fraser University, Vancouver, Canada
  • 2001-2002 Postdoctoral Fellow, Leiden University, The Netherlands
  • 2002- Royal Society University Research Fellow
  • 2002-2007 Lecturer & Reader, Dept of Mathematics, Imperial College London
  • 2007- Project Leader, Dept of Systems Biology, John Innes Centre
  • 2007- Honorary Professor, School of Computing Sciences, University of East Anglia

Martin Howard

Project Leader

Computational and Systems Biology

Contact details

Tel: +44 (0)1603 450892
martin.howard@jic.ac.uk

Research interests

The Howard group mathematically models biological systems at a variety of scales ranging from subcellular up to the level of embryonic development. Our core interest is in uncovering complex dynamics even in systems with few components and apparently simple interactions. We are especially interested in systems exhibiting pattern-forming and/or stochastic effects. Recent topics studied include protein localisation inside bacteria, fluctuations in morphogen gradients, mechanisms of robust signal transduction and epigenetic dynamics. Our approach is highly interdisciplinary, and relies heavily on the techniques of statistical physics, as well as on close collaboration with experimental groups.

Recent Publications

Angel A., Song J., Dean C., Howard M. (2011)
A polycomb-based switch underlying quantitative epigenetic memory
Nature 476 (7358) 105-108
DOI:10.1038/nature10241
Gerdes K., Howard M., Szardenings F. (2010)
Pushing and pulling in prokaryotic DNA segregation
Cell 141 (6) 927-942
DOI:10.1016/j.cell.2010.05.033
He F., Saunders T. E., Wen Y., Cheung D., Jiao R., Rein Ten Wolde P., Howard M., Ma J. (2010)
Shaping a morphogen gradient for positional precision
Biophysical Journal 99 (3) 697-707
DOI:10.1016/j.bpj.2010.04.073
Howard M., Gerdes K. (2010)
What is the mechanism of ParA-mediated plasmid segregation?
Molecular Microbiology 78 (1) 9-12
DOI:10.1111/j.1365-2958.2010.07316.x