Enrico Coen
Project Leader
Cell & Developmental Biology
Contact details
enrico.coen@jic.ac.uk
Research interests
How do small groups of cells in microscopic buds turn themselves into the diverse flower and leaf shapes we see around us? To answer this question we need to know how genes and growth interact to create tissue shapes during development, and how this process varies to produce such a remarkable range of forms. We use a highly integrative approach that combines molecular, genetic, imaging, population, ecological and computational approaches to address this problem, applying them to model systems such as Arabidopsis and Antirrhinum.
Selected Publications
Kim M., Cui M. L., Cubas P., Gillies A., Lee K., Chapman M. A., Abbott R. J., Coen E. (2008)
Regulatory genes control a key morphological and ecological trait transferred between species
Science 322 1116-1119
Recent Publications
Kuchen E. E., Fox S., de Reuille P. B., Kennaway R., Bensmihen S., Avondo J., Calder G. M., Southam P., Robinson S., Bangham A., Coen E. (2012)
Generation of leaf shape through early patterns of growth and tissue polarity.Science
335 (6072) 1092-6
DOI:10.1126/science.1214678
Robinson S., de Reuille P., Chan J., Bergmann D., Prusinkiewicz P., Coen E. S. (2011)
Generation of spatial patterns through cell polarity switching
Science 333 (6048) 1436-1440
Cui M. L., Copsey L., Green A., Bangham A., Coen E. (2010)
Quantitative control of organ shape by combinatorial gene activity
PLOS Biology 8 (11) e1000538
Rosas U., Barton N. H., Copsey L., Barbier de Reuille P., Coen E. (2010)
Cryptic variation between species and the basis of hybrid performance
PLOS Biology 8 (7) e1000429