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Tony Maxwell
Biological Chemistry Department
Tony Maxwell
DNA Helix
DNA Helix

My research concerns the structure and mechanism of DNA topoisomerases and associated proteins, in order to further our understanding of key biological processes in which they are involved, and to harness this knowledge for the development of therapeutic agents.

Current projects

  • Structure and mechanism of type II DNA topoisomerases (DNA gyrase, DNA
    topo IV, DNA topo VI, etc.)
  • DNA topoisomerases as drug targets - the molecular basis of antibiotic action
  • Novel strategies for developing antibiotics - exploitation of insect gut bacteria
  • Roles of topoisomerases in plants (Arabidopsis gyrase and topo VI)
  • Understanding supercoiling-dependent DNA recognition

Tony Maxwell - short biography

Inspiralis Ltd.

Inspiralis logoA range of products, including DNA gyrase, DNA substrates, antibodies and assay kits, can be bought through Inspiralis Ltd. For further details please visit the website, or contact Mrs Alison Howells, Inspiralis Ltd, Norwich Research Park, Colney, Norwich NR4 7UH, UK
Tel: 44 (0)1603 450924, Fax: 44 (0)1603 450923, Email:

New Edition of DNA Topology

DNA Topology - Bates and Maxwell
Available through all good bookshops, or direct from Oxford University Press

Other Opportunities

Enquiries from potential postgraduate and postdoctoral scientists interested in the Maxwell lab are always welcome.  Studentship and employment opportunities will be advertised in the popular and scientific press and will be posted on the JIC website:

John Innes Centre