Dr Lipeng Feng
Postdoctoral Scientist![](https://www.jic.ac.uk/app/uploads/2021/04/Lipeng-Feng-photo-300x300.jpg)
DNA gyrase, which is an essential enzyme in all bacteria, is a validated target for TB treatment, but resistance to the gyrase-targeted antibiotics (fluoroquinolones, FQs) is a serious problem.
The Maxwell lab’s previous work has shown that MfpA, a pentapeptide-repeat protein in mycobacteria, interacts with gyrase to modulate the activities of gyrase and protect the bacteria against FQs.
Currently, Feng is aimming to identify novel gyrase-interacting proteins using pull-down experiments and mass spectrometry and then investigate their roles in regulation of gyrase.