Bacteria make a remarkable array of natural products with potent biological activities.

Many of these molecules have important medicinal and agricultural applications, including antibiotics, antifungals and anti-cancer agents. For example, over two-thirds of clinically used classes of antibiotic are made by the actinomycetes, which are filamentous bacteria commonly found in the soil and associated with plants.

An understanding of the biosynthesis of these molecules can inform the discovery of new natural products with clinically-promising activities, such as antibiotics active towards multidrug-resistant bacteria or new anti-cancer agents.

Research in the Truman group is focused on three interrelated research areas:

  1. Biosynthesis of natural products
  2. Genome-led discovery of new natural products
  3. Understanding the role of natural products in nature

Selected Publications

See all of Dr Andrew Truman's publications


Informal enquiries to join the group from interested Postgraduate and Postdoctoral Scientists are always welcomed.