Dr Xiaoqi Feng
Cell and Developmental Biology
Most of our staple food comes from the product of flowering plant sexual reproduction, seeds. Therefore, a deeper understanding of this process is crucial for mankind.
Plant sexual reproduction is carried out by two highly specialized lines of cells, called the male and female sexual lineages. A fundamental but still unresolved question is how the reproductive function and fate are installed and maintained precisely in these cell lineages. We work at the interface of developmental biology and epigenetics to answer this question, using Arabidopsis thaliana as a primary model of study.
Employing a combination of molecular, genetic, imaging, epigenetic and genomic approaches, we aim to dissect the mechanisms by which genetic and epigenetic factors shape the function and fate determination of the male sexual lineage. Revealing novel genetic and epigenetic regulators and their crosstalk is essential for our knowledge of sexual reproduction, and, at a more fundamental level, important for understanding how the development of a specific lineage of cells is tightly controlled in the context of a plastic environment of plant development. Our work has implications for improving crop fertility and yield, and minimizing negative environmental impacts on crop production.
The male sexual lineage serves as a good paradigm for the study of plant lineage development, and Arabidopsis is an ideal model for epigenetic studies as it importantly tolerates significant epigenetic abnormalities. We welcome researchers interested in the genetic and epigenetic regulation of cell fate to join our group.
We are currently accepting applications for the positions of a postdoctoral researcher and a research assistant, and will continue to hire postdocs in 2015 and 2016. If you have passion in our research area, please feel encouraged to contact Dr. Xiaoqi Feng at email@example.com.
ContactTel: 01603 450684
Developmental Cell 24 (3) p215-25
Publisher’s version: 10.1016/j.devcel.2013.01.014
Science 337 p1360-4
Publisher’s version: 10.1126/science.1224839
Development 137 (14) p2409-16
Publisher’s version: 10.1242/dev.049320
Biochemical Society Transactions 38 (2) p571-6
Publisher’s version: 10.1042/BST0380571
Arabidopsis male sexual lineage exhibits more robust maintenance of CG methylation than somatic tissues.
Proceedings of the National Academy of Sciences of the United States of America 113 p15132-15137
Publisher’s version: 10.1073/pnas.1619074114
Proceedings of the National Academy of Sciences of the United States of America 113 p15138-15143
Publisher’s version: 10.1073/pnas.1619047114
Plant Cell Physiology 10.1093 ppcv087
Publisher’s version: 10.1093/pcp/pcv087
- Dr Hongbo Gao Postdoctoral Scientist
- Dr Jingyi Zhang Postdoctoral Scientist
- Dr Shengbo He Postdoctoral Scientist
- Mr James Walker Postgraduate Student
- Mr Billy Aldridge Postgraduate Student
BBSRC David Phillips Fellow, 2014-19
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