Prof Lars Ostergaard

Head of Department
Crop Genetics

Our laboratory works primarily on genetic and hormonal regulation of fruit development in the Brassicaceae family (including Arabidopsis, oilseed rape and Capsella). The group is developing genetic resources for Brassica research and is using both molecular genetics and functional genomics to study fruit growth.

Members of the Brassica genus include important crop plants such as oilseed rape (Brassica napus). They belong to the Brassicaceae family such as the model plant Arabidopsis. The close evolutionary relationship between Brassica species and Arabidopsis is reflected in similar plant architecture and organ morphology. The similarities in for example fruit development suggest that the underlying patterning mechanism is conserved. 

In addition to the academic satisfaction of understanding biological processes, the knowledge acquired during studies of fruit development among Brassicaceae provides an enormous potential for knowledge transfer to improve crop performance.  I am focused on pursuing such translational opportunities and hence developing tools for crop improvement.

John Innes Centre scientists use CRISPR technology to edit crop genes - subsequent generations contain no transgenes

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New research offers clue for 'the abominable mystery.' Auxin causes radial patterning in plant reproductive organs.

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Selected Publications

Girin T., Sorefan K., Ostergaard L. (2009)

Meristematic sculpting in fruit development

Journal of Experimental Botany 60 p1493-1502

Publisher’s version: 10.1093/jxb/erp031

Recent Publications

Simonini S., Deb J., Moubayidin L., Stephenson P., Valluru M., Freire-Rios A., Sorefan K., Weijers D., Friml J., Ostergaard L. (2016)

A noncanonical auxin-sensing mechanism is required for organ morphogenesis in Arabidopsis

Genes & Development 30 p2286-2296

Publisher’s version: 10.1101/gad.285361.116

Eldridge T., Langowski L., Stacey N., Jantzen F., Moubayidin L., Sicard A., Southam P., Kennaway R., Lenhard M., Coen E. S., Ostergaard L. (2016)

Fruit shape diversity in the Brassicaceae is generated by varrying patterns of anisotropy

Development 143 p3394-3406

Publisher’s version: 10.1242/dev.135327

Langowski L., Stacey N., Østergaard L. (2016)

Diversification of fruit shape in the Brassicaceae family.

Plant reproduction DOI 10.1007/s00497-016-0278-6 p1-15

Publisher’s version: 10.1007/s00497-016-0278-6

Lawrenson T., Shorinola O., Stacey N., Li C., Ostergaard L., Patron N., Uauy C., Harwood W. (2015)

Induction of targeted, heritable mutations in barley and Brassica oleracea using RNA-guided Cas9 nuclease.

Genome Biology 16 p258

Publisher’s version: 10.1186/s13059-015-0826-7

Moubayidin L., Østergaard L. (2015)

Symmetry matters.

New Phytologist 207 p551558

Publisher’s version: 10.1111/nph.13526

View All

Lars Ostergaard

  • Saleha Bakht Research Assistant
  • Friederike Jantzen Visiting Worker
  • Carrie Peplow Postgraduate Student
  • Marie Bruser Postgraduate Student
  • Xinran Li Postdoctoral Scientist
  • Dr Lukasz Langowski Postdoctoral Scientist
  • Sara Simonini Postdoctoral Scientist
  • Dr Laila Moubayidin Postdoctoral Scientist
  • Nicola Stacey Research Assistant
  • Pauline Stephenson Research Assistant


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