Martin is a research assistant with the Field group and responsible for day to day support and training in the lab.
Martin received training in natural product chemistry and later continued to specialise in insect endocrine system and chemical ecology.
His early work focused on design and synthesis of insect juvenile hormone analogues and defence alkaloids and their use in insect pest management. Within the Field group Martin’s work has been centred around chemical glycobiology.
Martin has developed extensive expertise in preparative and analytical carbohydrate chemistry; in carbohydrate-active enzymes and their characterisation, exploitation and inhibition; in surface chemistry and biophysics of carbohydrate-active enzymes; and in elucidation of in vivo function of enzymes involved in carbohydrate metabolism.
The main area of Martin’s research is nucleotide diphospho sugars (NDP-sugars) covering various aspects of their chemical and enzymatic synthesis, chromatographic purification, design and synthesis of NDP-sugar analogues as molecular probes, biosynthesis, and metabolic profiling.
Examples of experimental techniques to study carbohydrates available in Field’s lab include: High-Performance Anion-Exchange Chromatography Coupled with Pulsed Electrochemical Detection (HPAEC-PAD) High-Performance Liquid Chromatography Coupled with Charged Aerosol Detector (HPLC-CAD) Gel Permeation Chromatography (GPC) Capillary Electrophoresis (CE).
O'Neill E. C., Trick M., Hill L., Rejzek M., Dusi R. G., Hamilton C. J., Zimba P. V., Henrissat B., Field R. A. (2015)The transcriptome of Euglena gracilis reveals unexpected metabolic capabilities for carbohydrate and natural product biochemistry.Molecular Biosystems (11)Publisher's version: 1742-2051
Wagstaff B. A., Hems E. S., Rejzek M., Pratscher J., Brooks E., Kuhaudomlarp S., O'Neill E. C., Donaldson M. I., Lane S., Currie J., Hindes A. M., Malin G., Murrell J. C., Field R. A. (2018)Insights into toxic Prymnesium parvum blooms: the role of sugars and algal virusesBiochemical Society TransactionsPublisher's version: 0300-5127
Rejzek M., Hill L., Hems E. S., Kuhaudomlarp S., Wagstaff B. A., Field R. A. (2017)Profiling of Sugar NucleotidesPublisher's version: 0076-6879