Dr Jacob Malone

Project Leader
Molecular Microbiology

Jake is a molecular microbiologist, interested in the signalling pathways that control plant colonisation and infection by Pseudomonas species.

He investigates how bacterial signal transduction pathways respond to inputs from the environment, and how this regulates bacterial behaviour.

Jake’s research is focussed on combatting agriculturally relevant plant diseases, both caused, and suppressed, by Pseudomonas.

Jake also investigates the effect of plant genotype on microbial communities within the soil, and how this may be exploited for agricultural benefit.

  • Pseudomonas signal transduction in response to environmental stimuli
  • Bacterial infection and colonisation mechanisms in both plants and humans
  • Identifying bacterial output pathways that suppress plant diseases

New “movie” technique reveals bacterial signalling in sharper resolution

read more

Discovery shows soil dwelling bacteria adapt to richer or poorer conditions in marriage of convenience with plants

read more

John Innes Centre scientists disable infectious bacteria by removing key protein

read more

Wheat choice has lasting effect on soil health & wheat yield

read more

Recent Publications

Grenga L., Chandra G., Saalbach G., Galmozzi C. V., Kramer G., Malone J. (2017)

Analyzing the Complex Regulatory Landscape of Hfq – an Integrative, Multi-Omics Approach

Frontiers in Microbiology 8 p1784

Publisher’s version: 10.3389/fmicb.2017.01784

Campilongo R., Fung R. K. Y., Little R. H., Grenga L., Trampari E., Pepe S., Chandra G., Stevenson C. E. M., Roncarati D., Malone J. G. (2017)

One ligand, two regulators and three binding sites: How KDPG controls primary carbon metabolism in Pseudomonas.

PLoS Genetics 13 pe1006839

Publisher’s version: 10.1371/journal.pgen.1006839

Grenga L., Little R. H., Malone J. (2017)

Quick Change - post-transcriptional regulation in Pseudomonas.

FEMS Microbiology Letters n/a pn/a

Publisher’s version: 10.1093/femsle/fnx125

Mauchline T. H., Malone J. G. (2017)

Life in earth - the root microbiome to the rescue?

Current Opinion in Microbiology 37 p23-28

Publisher’s version: 10.1016/j.mib.2017.03.005

Kirkpatrick C. L., Lesouhaitier O., Malone J. G., An S. Q., Caly D. L. (2017)

Interaction and signalling networks: a report from the fourth 'Young Microbiologists Symposium on Microbe Signalling, Organisation and Pathogenesis'.

Microbiology (Reading, England) 163 p4-8

Publisher’s version: 10.1099/mic.0.000401

View All

Jacob Malone

  • Dr Richard Little Research Assistant
  • Eleftheria Trampari Postgraduate Student
  • Dr Rosaria Campilongo Visiting Worker
  • Dr Lucia Grenga Visiting Worker
  • Kieran Rustage Undergraduate Project Student

Media

For media enquiries, please contact the JIC communications team 01603 450962, jic.communications@jic.ac.uk

Expertise: Bacterial signalling, plant growth-promoting bacteria, biocontrol

JIC Cookie Policy. We use cookies on this site to enhance your user experience. By clicking any link on this page you are giving your consent for us to set cookies. You can find out more about the cookies by clicking here.

Accept cookies