Friday Seminar – ‘Mechanisms and functions of RNA NAD+ capping’

Our next Friday Seminar speaker is Professor Xuemei Chen from the University of California, Riverside.

Email jic.fridayseminars@jic.ac.uk to request access to the recording.

Abstract

Eukaryotic messenger RNAs are known to have an m7G cap that stabilises them and promotes translation.

The cellular metabolite and redox agent, NAD+, has recently been recognised as an alternative mRNA cap.

Professor Chen will describe methods to profile NAD+-capped RNAs and discuss how the NAD+ cap is installed and removed, and what the NAD+ cap might do at the molecular and biological levels.

Professor Xuemei Chen biography

Xuemei Chen received a B.S. degree from Peking University, China and a doctorate from Cornell University, USA.

After postdoctoral training at California Institute of Technology, she started her assistant professor position in 1999 at the Waksman Institute at Rutgers University. She was promoted to associate professor in 2005 and won the Board of Trustees Research Fellowship for Scholarly Excellence at Rutgers University. She moved to University of California, Riverside in 2005 as an associate professor and was promoted to full professor in 2009 and distinguished professor in 2013.

In 2006, she received the prestigious Charles Albert Shull award from American Society of Plant Biologists. In 2011, she was elected an AAAS Fellow. She was an HHMI-GBMF investigator from 2012 to 2017. In 2013, she was elected into the US National Academy of Sciences.

Her work has focused on flower development, small RNAs, and RNA modifications in plants.

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