Directory

Dr Paul Nicholson

Project Leader
Crop Genetics

Our lab is identifying and characterising resistances to two disease complexes of cereals. 

Fusarium head blight (FHB) of cereals reduces yield and contaminates grain with harmful mycotoxins while, at the other end of the plant eyespot damages the stem base, causing plants to fall over, again leading to yield loss. Identifying resistance to both diseases is difficult because resistance is quantitative with varieties being only more or less susceptible and never completely resistant. Improving FHB resistance is particularly difficult because of interactions with the environment and trade-off between resistance and agronomically important traits such as plant height. 

We have identified novel FHB and eyespot resistances and are characterising the most potent of these with the aim of cloning the genes responsible in order to understand how resistance functions. We are actively engaged with plant breeders through our development of molecular markers to these resistances that enables breeders to incorporate them into new varieties.

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Recent Publications

Burt C., Steed A., Gosman N., Lemmens M., Bird N., Ramirez Gonzalez R., Holdgate S., Nicholson P. (2015)

Mapping a Type 1 FHB resistance on chromosome 4AS of Triticum macha and deployment in combination with two Type 2 resistances.

Theoretical and Applied Genetics 128 p1725-38

Publisher’s version: 10.1007/s00122-015-2542-9

Burt C., Steed A., Gosman N., Bird N., Ramirez-Gonzalez N., Lemmens M., Holdgate S., Nicholson P. (2015)

Mapping a Type 1 FHB resistance on chromosome 4AS of Triticum macha and deployment in combination with two Type 2 resistances.

Theoretical and Applied Genetics

Publisher’s version: 10.1007/s00122-015-2542-9

Goddard R., Peraldi A., Ridout C., Nicholson P. (2014)

Enhanced Disease Resistance Caused by BRI1 Mutation Is Conserved Between Brachypodium distachyon and Barley ( Hordeum vulgare )

Molecular Plant-Microbe Interactions 27 p1095-1106

Publisher’s version: 10.1094/MPMI-03-14-0069-R

McGrann G. R. D., Steed A., Burt C., Goddard R., LaChaux C., Bansal A., Corbitt M., Gornial K., Nicholson P., Brown J. K. M. (2014)

Contribution of the drought tolerance-related Stress-responsive NAC 1 transcription factor to resistance of barley to Ramularia leaf spot

Molecular Plant Pathology 16 p201209

Publisher’s version: 10.1111/mpp.12173

Brown J. K. M., Andrivon D., Collinge D. B., Nicholson P. (2013)

Fitness Costs and Trade-offs in Plant Disease

Plant Pathology 62 (Suppl. 1) p1-1

Publisher’s version: 10.1111/ppa.12124

View All

Paul Nicholson

  • Martha Clarke Research Assistant
  • Mark Collins Lab Attendant
  • Joe Nicholson Lab Attendant
  • Dr Sarah De Vos Postdoctoral Scientist
  • Rachel Goddard Postgraduate Student
  • Andrew Steed Research Assistant

Media

For media enquiries, please contact the JIC communications team 01603 450962, jic.communications@jic.ac.uk

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