Dr Cristobal Uauy

Project Leader
Crop Genetics

Our lab seeks to identify genes underlying wheat QTL with significant agronomic impact, understand the mechanism by which they function and using this knowledge, facilitate their effective deployment into modern breeding varieties.

We are currently using molecular genetics approaches to:

  • identify the genes responsible for key yield and quality traits in UK wheat germplasm,
  • understand the interaction between wheat and the yellow rust fungal pathogen
  • develop genetic resources to enable effective translational research from model systems to crop species,
  • enhance the pipeline to translate this new knowledge into improved wheat varieties for growers, industry and consumers.


Tel: 01603 450195

Global surveillance leaves Cereal Killers nowhere to hide

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New world-class scientific collaboration to use genomics to combat devastating crop rusts

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JIC and TGAC identify new genetic markers to combat yellow rust disease in wheat

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Dr Cristobal Uauy awarded an SEB President's Medal

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Selected Publications

Uauy C., Paraiso F., Colasuonno P., Tran R., Tsai H., Berardi S., Comai L., Dubcosvky J. (2009)

A modified TILLING approach to detect induced mutations in tetraploid and hexaploid wheat

BMC Plant Biology 9 pArt: 115

Fu D., Uauy C., Blechl A., Dubcovsky J. (2007)

RNA interference for wheat functional gene analysis.

Transgenic Research 16 (6) p689-701

Publisher’s version: 10.1007/s11248-007-9150-7

Distelfeld A., Uauy C., Fahima T., Dubcovsky J. (2006)

Physical map of the wheat high-grain protein content gene Gpc-B1 and development of a high-throughput molecular marker.

New Phytologist 169 (4) p753-63

Publisher’s version: 10.1111/j.1469-8137.2005.01627.x

Uauy C., Distelfeld A., Fahima T., Blechl A., Dubcovsky J. (2006)

A NAC Gene regulating senescence improves grain protein, zinc, and iron content in wheat.

Science 314 (5803) p1298-301

Publisher’s version: 10.1126/science.1133649

Uauy C., Brevis J. C., Dubcovsky J. (2006)

The high grain protein content gene Gpc-B1 accelerates senescence and has pleiotropic effects on protein content in wheat.

Journal of Experimental Botany 57 (11) p2785-94

Publisher’s version: 10.1093/jxb/erl047

Recent Publications

Segovia V., Hubbard A., Craze M., Bowden S., Wallington E., Bryant R., Greenland A., Bayles R., Uauy C. (2014)

Yr36 confers partial resistance at temperatures below 18° C to UK isolates of Puccinia striiformis

Phytopathology 104 p871-878

Publisher’s version: 10.1094/PHYTO-10-13-0295-R

Borrill P., Connorton J., Balk J., Miller T., Sanders D., Uauy C. (2014)

Biofortification of wheat grain with iron and zinc: integrating novel genomic resources and knowledge from model crops

Frontiers in Plant Science 5 (53)

Publisher’s version: 10.3389/fpls.2014.00053

Bryant R. M., McGrann G. R. D., Mitchell A. R., Schoonbeek H., Boyd L. A., Uauy C., Dorling S., Ridout C. (2014)

A change in temperature modulates defence to yellow (stripe) rust in wheat line UC1041 independently of resistance gene Yr36

BMC Plant Biology 14 p10

Publisher’s version: 10.1186/1471-2229-14-10

Ramirez-Gonzalez R., Segovia V., Bird N., Fenwick P., Holdgate S., Berry S., Jack P., Caccamo M., Uauy C. (2014)

RNA-Seq bulked segregant analysis enables the identification of high-resolution genetic markers for breeding in hexaploid wheat

Plant Biotechnology Journal n/a pn/a

Publisher’s version: n/a

Hazard B., Zhang X., Colasuonno P., Uauy C., Beckles D., Dubcovsky J. (2013)

Induced mutations in the SBE genes increase amylose and resistant starch content in durum wheat

Crop Science 52 p1754-1766

View All

Cristobal Uauy

  • Nikolai Adamski Postdoctoral Scientist
  • James Simmonds Research Assistant
  • Oluwaseyi Shorinola Postgraduate Student
  • Dr Marianna Pasquariello Research Assistant
  • Dr Clare Lewis Research Assistant
  • Amelia Frizell-Armitage Postgraduate Student
  • Jemima Florence Brinton Postgraduate Student
  • Dr Philippa Borrill Postdoctoral Scientist
  • Tobin Florio Research Assistant


For media enquiries, please contact the JIC communications team 01603 450962,

Media experience: print media and radio interviews (recorded preferred / live or recorded)

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