Marcelo is part a network of UK and Brazilian researchers working closely together as a Virtual Joint Centre to develop innovative technologies to increase crop productivity in Brazil, using diazotrophic bacteria as a source of fixed nitrogen.
The major aim of the project is to exploit current knowledge of nitrogen regulation in nitrogen fixing bacteria to engineer strains, which excrete ammonium to benefit crop growth.
The group aim to design engineered bacteria with enhanced nitrogen fixation in which the process of ammonia biosynthesis by nitrogenase is uncoupled from its assimilation, thus enabling export of surplus fixed nitrogen
Batista M. B., Dixon R. (2019)Manipulating nitrogen regulation in diazotrophic bacteria for agronomic benefit.Biochemical Society Transactions (47(2))Publisher's version: 0300-5127
Raittz RT,Reginatto De Pierri C,Maluk M,Bueno Batista M, Carmona M,Junghare M,Faoro H,Cruz LM,Battistoni F,Souza ED,Pedrosa FO, Chen WM,Poole PS,Dixon R,James EK (2021)Comparative Genomics Provides Insights into the Taxonomy of Azoarcus and Reveals Separate Origins of Nif Genes in the Proposed Azoarcus and Aromatoleum GeneraGenes (12,71)Publisher's version: 2073-4425
Batista M. B., Chandra G., Monteiro R. A., de Souza E. M., Dixon R. (2018)Hierarchical interactions between Fnr orthologs allows fine-tuning of transcription in response to oxygen in Herbaspirillum seropedicaeNucleic Acids Research (46 (8))Publisher's version: 1362-4962