Dr Clare Stevenson
Senior Scientist
Clare’s role is split between the Protein Crystallography and Biophysical Analysis platform.
Clare works for David Lawson on the Protein Crystallography platform. The Protein Crystallography team use X-ray crystallography to reveal the atomic details of biological systems providing deep insights into molecular interactions, gene regulation, enzyme mechanism, protein function and protein evolution.
She manages the Biophysical Analysis platform which has two techniques (Surface Plasmon Resonance and Isothermal Titration Calorimetry) that can be used to study a wide range of biomolecular interactions and a third technique Circular Dichroism spectroscopy) that can be used to look at the secondary structure of proteins.
Clare is also the lead for the Technician Commitment at the John Innes Centre.
Selected Publications
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Tran N. T., Stevenson C., Som N., Thanapipatsiri A., Jalal A., Le T. (2018)Permissive zones for the centromere-binding protein ParB on the Caulobacter crescentus chromosomeNucleic Acids Research (46)Publisher's version: 0305-1048
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Ghilarov D., Serebryakova M., Stevenson C. E. M., Hearnshaw S. J., Volkov D. S., Maxwell A., Lawson D. M., Severinov K. (2017)The Origins of Specificity in the Microcin-Processing Protease TldD/E.Structure (25)Publisher's version: 0969-2126
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Stevenson C. E., Assaad A., Chandra G., Le T. B., Greive S. J., Bibb M. J., Lawson D. M. (2013)Investigation of DNA sequence recognition by a streptomycete MarR family transcriptional regulator through surface plasmon resonance and X-ray crystallography.Nucleic Acids Research (41)Publisher's version: 0305-1048