Dr Veronica Grieneisen
Computational and Systems Biology
Veronica’s research uses our current understanding of subcellular interactions to look at what is possible in terms of tissue-level patterning mechanisms to develop robust plants which can respond to a changing environment.
Her research explores cell polarity and hormonal patterns and fluxes, and how chemicals move through plant tissue.
She uses mathematical and computational methodology to understand genetic networks and pathways and to develop models and knowledge of plant growth, architecture and environmental interactions.
- Mathematical and computational modelling of biological processes
- Understanding the mechanisms which control tissue level patterning
- Environmental influences on plant development
The lab aims to understand spatial regulation of intracellular cell polarity, cell shape changes, and intercellular polarity coupling and signalling in morphogenesis.
To achieve this, they use a combination of approaches: mathematical and computational methods, experiments in Arabidopsis, and (most recently), 'experiences' with autonomous agents (robot swarms).
In particular, the group wish to unravel the complexity of the feedbacks between subcellular mechanisms of cell polarity and tissue-level patterning mechanisms, focusing on hormonal patterning, genetic regulatory networks, biophysical interactions, and the tight-interaction between plant development and the environment.
From a theoretical standpoint, their studies allow us to gain new insights on mechanisms of biological pattern formation and principles of auto-organisation. From a practical point of view, they are interested in understanding how plants control their growth and architecture, and how they optimally regulate their intake of nutrients.
Their multi-modelling strategy captures biological processes at different levels – molecular and genetic levels, subcellular properties, cells and organs – allowing them to interact under certain hypothesis and within a 'controlled' system (which experiments do not easily permit).
Sound new technique tunes into the shifting shapes of biologyread more
Life in the fast lane: how plants avoid traffic jamsread more
Development 140 p2061-74
Publisher’s version: 10.1242/dev.062984
Publisher’s version: 10.1371/journal.pbio.2005952
Development (Cambridge, England)
Publisher’s version: 10.1242/dev.156778
Development (Cambridge, England) 144 p4386-4397
Publisher’s version: 10.1242/dev.157073
Auxin minimum triggers the developmental switch from cell division to cell differentiation in the Arabidopsis root.
Proceedings of the National Academy of Sciences of the United States of America 114 pE7641-E7649
Publisher’s version: 10.1073/pnas.1705833114
Publisher’s version: 10.7554/eLife.27038
- Dr Ross Carter Postdoctoral Scientist
- Nadiatul Radzman Postdoctoral Scientist
- Martin Hinsch Postdoctoral Scientist
- Dr Susana Sauret-Gueto Research Assistant
President's Medalist of the Society of Experimental Biology, 2011
Hugo de Vries Award of the Hugo de Vries Foundation and the Royal Dutch Botanical Society, 2009
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