John Innes Centre

Prof Giles Oldroyd

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Curriculum Vitae

  • 1990-1994 University of East Anglia, Norwich, UK. 1st class B.S. Honours Biology
  • 1994-1998 University of California, Berkeley. PhD, Plant Biology,
  • 1998-2002 Postdoctoral researcher in the laboratory of Dr. Sharon Long, Howard Hughes Medical Institute Stanford University.
  • 2002 - present David Phillips Fellow and Project leader at the John Innes Centre

Giles Oldroyd

Project Leader

Cell & Developmental Biology

Contact details

giles.oldroyd@jic.ac.uk

Research interests

Legumes form symbiotic interactions with rhizobial bacteria that lead to the formation of nodules on the roots of the host plant. The bacteria reside inside the cells within the nodule and convert molecular dinitrogen (atmospheric nitrogen) to ammonia, a form of nitrogen readily available to the plant. The initial stages of this interaction involve molecular communication between the plant and the bacteria. Nod factor is a critical signalling molecule generated by the bacteria that activates key responses in the plant. The work in this laboratory looks at a number of aspects of the legume/rhizobial symbiosis with a focus on Nod factor perception and signal transduction in the plant. We work on the model legume Medicago truncatula which interacts with the rhizobial species Sinorhizobium meliloti.

Current Vacancies

Post No.Job TitleClosing Date
Postdoctoral Scientists06-May-2014

Recent Publications

Yu N., Luo D., Zhang X., Liu J., Wang W., Jin Y., Dong W., Liu J., Liu H., Yang W., Zeng L., Li Q., He Z., Oldroyd G. E., Wang E. (2014)
A DELLA protein complex controls the arbuscular mycorrhizal symbiosis in plants.
Cell Research 24 (1) 130-3
DOI:10.1038/cr.2013.167
Charpentier M., Oldroyd G. E. (2013)
Nuclear calcium signaling in plants
Plant Physiology 163 (2) 496-503
DOI:10.1104/pp.113.220863
Charpentier M., Vaz Martins T., Granqvist E., Oldroyd G., Morris R. (2013)
The role of DMI1 in establishing Ca ( 2+) oscillations in legume symbioses.
Plant Signaling and Behaviour 8 (2) e22894
Domonkos A., Horvath B., Marsh J. F., Halasz G., Ayaydin F., Oldroyd G. E., Kalo P. (2013)
The identification of novel loci required for appropriate nodule development in Medicago truncatula.
BMC Plant Biology 13 157
DOI:10.1186/1471-2229-13-157
Guan D., Stacey N., Liu C., Wen J., Mysore K. S., Torres-Jerez I., Vernié T., Tadege M., Zhou C., Wang Z. Y., Udvardi M. K., Oldroyd G. E., Murray J. D. (2013)
Rhizobial infection is associated with the development of peripheral vasculature in nodules of Medicago truncatula.
Plant Physiology 162 (1) 107-15
DOI:10.1104/pp.113.215111
Miller J. B., Pratap A., Miyahara A., Zhou L., Bornemann S., Morris R. J., Oldroyd G. E. (2013)
Calcium/Calmodulin-dependent protein kinase is negatively and positively regulated by calcium, providing a mechanism for decoding calcium responses during symbiosis signaling.
Plant Cell 25 (12) 5053-66
DOI:10.1105/tpc.113.116921
Morieri G., Martinez E. A., Jarynowski A., Driguez H., Morris R., Oldroyd G. E. D., Downie J. A. (2013)
Host-specific Nod-factors associated with Medicago truncatula nodule infection differentially induce calcium influx and calcium spiking in root hairs
New Phytologist 200 (3) 656-662
DOI:10.1111/nph.12475
Oldroyd G. E. (2013)
Speak, friend, and enter: signalling systems that promote beneficial symbiotic associations in plants.
Nature Reviews Microbiology 11 (4) 252-63
DOI:10.1038/nrmicro2990
Roberts N. J., Morieri G., Kalsi G., Rose A., Stiller J., Edwards A., Xie F., Gresshoff P. M., Oldroyd G. E., Downie J. A., Etzler M. E. (2013)
Rhizobial and mycorrhizal symbioses in Lotus japonicus require lectin nucleotide phosphohydrolase, which acts upstream of calcium signaling.
Plant Physiology 161 (1) 556-67
DOI:10.1104/pp.112.206110
Routray P., Miller J. B., Du L., Oldroyd G., Poovaiah B. W. (2013)
Phosphorylation of S344 in the calmodulin-binding domain negatively affects CCaMK function during bacterial and fungal symbioses.
Plant Journal 76 (2) 287-96
DOI:10.1111/tpj.12288
Cerri M. R., Frances L., Laloum T., Auriac M. C., Niebel A., Oldroyd G. E., Barker D. G., Fournier J., de Carvalho-Niebel F. (2012)
Medicago truncatula ERN transcription factors: regulatory interplay with NSP1/NSP2 GRAS factors and expression dynamics throughout rhizobial infection.
Plant Physiology 160 (4) 2155-72
DOI:10.1104/pp.112.203190
Gobbato E., Marsh J. F., Vernié T., Wang E., Maillet F., Kim J., Miller J. B., Sun J., Bano S. A., Ratet P., Mysore K. S., Dénarié J., Schultze M., Oldroyd G. E. (2012)
A GRAS-type transcription factor with a specific function in mycorrhizal signaling
Current Biology 22 (23) 2236-2241
DOI:10.1016/j.cub.2012.09.044
Granqvist E., Wysham D., Hazledine S., Kozlowski W., Sun J., Charpentier M., Vaz Martins T., Haleux P., Tsaneva-Atanasova K., Downie J. A., Oldroyd G. E., Morris R. J. (2012)
Buffering capacity explains signal variation in symbiotic calcium oscillations.
Plant Physiology 160 2300-2310
DOI:10.1104/pp.112.205682
Swainsbury D. J. K., Zhou L., Oldroyd G. E. D., Bornemann S. (2012)
Calcium ion binding properties of Medicago truncatula calcium/calmodulin-dependent protein kinase
Biochemistry 51 (35) 6895-6907
DOI:10.1021/bi300826m
Wang E., Schornack S., Marsh J. F., Gobbato E., Schwessinger B., Eastmond P., Schultze M., Kamoun S., Oldroyd G. E. (2012)
A common signaling process that promotes mycorrhizal and oomycete colonization of plants
Current Biology 22 (23) 2242-2246
DOI:10.1016/j.cub.2012.09.043
Xie F., Murray J. D., Kim J., Heckmann A. B., Edwards A., Oldroyd G. E., Downie J. A. (2012)
Legume pectate lyase required for root infection by rhizobia.
Proceedings of the National Academy of Sciences of the United States of America 109 (2) 633-638
DOI:10.1073/pnas.1113992109