Research theme: Structural Biology
My research seeks to understand biological systems at the molecular level and thereby provide deep insights into macromolecular interactions, gene regulation, enzyme mechanisms and protein evolution.
Main research areas
- Ligand-responsive transcriptional control in Streptomycetes
- Antibiotic biosynthetic pathways in Streptomycetes
- Molecular basis of action of antibiotics against DNA topoisomerases
- The structural enzymology of carbohydrate metabolism
The ReDCaT Chip
We (Clare Stevenson, Sandra Greive and Dave Lawson) have recently formulated the Re-usable DNA Capture Technology (ReDCaT) Chip, which uses surface plasmon resonance to quickly and cheaply analyze protein-DNA interactions. This is now being offered as a service through Inspiralis Ltd (www.inspiralis.com).
Opportunities
Enquiries from potential postgraduate and postdoctoral scientists interested in the Lawson lab are always welcome. Studentship and employment opportunities will be advertised in the popular and scientific press and will be posted on the JIC website:
