Professor Wendy Harwood
I lead the Crop Transformation Group that develops and delivers efficient crop genetic modification and genome editing. We use transformation-based technologies to help understand gene function and develop new and improved protocols for genome engineering in crops. The group is also responsible for the BRACT facility that provides crop transformation resources to the research community (www.bract.org).
Crops of interest include wheat, barley, Brassica napus and Brassica oleracea. Efficient Agrobacterium-mediated transformation protocols have been developed for each of these crops but work continues to extend the range of genotypes that can be transformed and to further improve efficiencies. New technologies, including genome editing using the CRISPR/cas system, have been successfully used in barley and Brassica oleracea and are being investigated in other crops. The group also has an interest in engineering tolerance to drought and salt stress in cereals.
The BRACT transformation facility helps to meet the demand for crop transformation as a research tool to verify gene function. As well as providing a full crop transformation service BRACT provides constructs, training, opportunities for collaboration and hosts visitors wishing to carry out their own transformation experiments. I am also active in public engagement and an Honorary Lecturer at the University of East Anglia.
ContactTel: 01603 450609
Horticultural Science 51 p558-562
Induction of targeted, heritable mutations in barley and Brassica oleracea using RNA-guided Cas9 nuclease.
Genome Biology 16 p258
Publisher’s version: 10.1186/s13059-015-0826-7
Critical Reviews in Biotechnology 1 p1-9
Publisher’s version: 10.3109/07388551.2015.1055707
For media enquiries, please contact the JIC communications team 01603 450962, firstname.lastname@example.org
Expertise: Genetic modification technologies, GM safety, wheat, barley
Experience: TV, radio, presentations, discussion sessions, demonstrations