Prof Enrico Coen

Project Leader
Cell and Developmental Biology

How do small groups of cells in microscopic buds turn themselves into the diverse flower and leaf shapes we see around us? To answer this question we need to know how genes and growth interact to create tissue shapes during development, and how this process varies to produce such a remarkable range of forms.

We use a highly integrative approach that combines molecular, genetic, imaging, population, ecological and computational approaches to address this problem, applying them to model systems such as Arabidopsis and Antirrhinum.

Through collaborations with Andrew Bangham, Veronica Grieneisen and Stan Marée, we have been able to arrive at mechanistic models for how complex tissue shapes may be generated through combinatorial interactions between genes, polarity and local growth properties. We also collaborate with population geneticist Nick Barton to understand the evolution of complex traits in natural populations and species of Antirrhinum.

Professor Enrico Coen wins premier Royal Society Medal

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JIC Historical Collections images available through the Mary Evans Picture Library

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Watch online: Public Lecture by Professor Enrico Coen FRS at Edinburgh Science Festival

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Royal Society Winton Prize for Science Books 2013

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Selected Publications

Abley K., De Reuille P. B., Strutt D., Bangham A., Prusinkiewicz P., Maree A. F., Grieneisen V. A., Coen E. (2013)

An intracellular partitioning-based framework for tissue cell polarity in plants and animals.

Development 140 (10) p2061-74

Publisher’s version: 10.1242/dev.062984

Sauret-Güeto S., Schiessl K., Bangham A., Sablowski R., Coen E. (2013)

JAGGED Controls Arabidopsis Petal Growth and Shape by Interacting with a Divergent Polarity Field.

PLoS Biology 11 (4) pe1001550

Publisher’s version: 10.1371/journal.pbio.1001550

Kuchen E. E., Fox S., de Reuille P. B., Kennaway R., Bensmihen S., Avondo J., Calder G. M., Southam P., Robinson S., Bangham A., Coen E. (2012)

Generation of leaf shape through early patterns of growth and tissue polarity.

Science 335 (6072) p1092-6

Publisher’s version: 10.1126/science.1214678

Robinson S., de Reuille P., Chan J., Bergmann D., Prusinkiewicz P., Coen E. S. (2011)

Generation of spatial patterns through cell polarity switching

Science 333 (6048) p1436-1440

Kim M., Cui M. L., Cubas P., Gillies A., Lee K., Chapman M. A., Abbott R. J., Coen E. (2008)

Regulatory genes control a key morphological and ecological trait transferred between species

Science 322 p1116-1119

Recent Publications

Raimundo J., Sobral R., Bailey P., Azevedo H., Galego L., Almeida J., Coen E., Costa M. M. (2013)

A subcellular tug of war involving three MYB-like proteins underlies a molecular antagonism in Antirrhinum flower asymmetry.

Plant Journal 10 p12225

Publisher’s version: 10.1111/tpj.12225

Green A. A., Kennaway R. J., Hanna A. I., Bangham A. J., Coen E. (2010)

Genetic control of organ shape and tissue polarity

PLOS Biology 8 (11) pe1000537

Cui M. L., Copsey L., Green A., Bangham A., Coen E. (2010)

Quantitative control of organ shape by combinatorial gene activity

PLOS Biology 8 (11) pe1000538

Rosas U., Barton N. H., Copsey L., Barbier de Reuille P., Coen E. (2010)

Cryptic variation between species and the basis of hybrid performance

PLOS Biology 8 (7) pe1000429

Feng X., Wilson Y., Bowers J., Kennaway R., Bangham A., Hannah A., Coen E., Hudson A. (2009)

Evolution of allometry in Antirrhinum

The Plant Cell 21 p2999-3007

View All

Enrico Coen

  • Catherine Mansfield Postgraduate Student
  • Dr Christopher Whitewoods Postdoctoral Scientist
  • Dr Annabel Whibley Postdoctoral Scientist
  • Xana Verweij Postdoctoral Scientist
  • Dr Paul Southam Postdoctoral Scientist
  • Annis Richardson Postgraduate Student
  • Dr Jake Newman Postdoctoral Scientist
  • Karen Lee Research Assistant
  • Richard Kennaway Senior Scientist
  • Samantha Fox Research Assistant
  • Mabon Elis Postgraduate Student
  • Lucy Copsey Research Assistant
  • Claire Bushell Postgraduate Student
  • Dr Des Bradley Research Assistant
  • Alice Dore Lab Attendant


European Molecular Biology Organisation Young Investigator committee member, 2015-18

Elected President of the Genetics Society, 2012

Dawin Medal, 2004

Commander of the British Empire, 2003

Foreign Associate of the US National Academy of Science, 2001

Fellow of the Royal Society, 1998

Linnean Gold Medal, 1997

European Molecular Biology Organisation Medal, 1996

Science for Art Prize, LVMH Moet Hennessy, France, 1996

Elected Member of the European Molecular Biology Organisation, 1991


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