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Research Assistant (Ghilarov Group)

We’re looking for a Research Assistant to join the Ghilarov Group working on the molecular aspects of antibiotic biosynthesis, function and resistance.

The Ghilarov group uses cryo-EM to study antibiotic biosynthesis, function and resistance. Further information is available at

The role

The main purpose of the role will be to carry out a range of biochemical experiments to elucidate the mechanism of action of a new type of gyrase inhibitors.

The Research Assistant will establish the mechanism of action of a novel topoisomerase inhibitor. The project involves biochemical activity assays and cryo-EM studies of Escherichia coli DNA gyrase.

We will provide training in biochemical assays involving DNA gyrase, protein purification and sample preparation for cryo-electron microscopy.

The ideal candidate

You will have a BSc in biomedical science. You will have in-depth knowledge of protein & nucleic acid biochemistry, protein purification (AKTA), molecular genetics (site-directed mutagenesis) and an interest in structural biology/cryo-EM.

Additional information

We welcome applications from candidates seeking job-share, part-time or other flexible working arrangements.

Further information and details of how to apply, can be found here or contact the Human Resources team on 01603 450462 or quoting reference 1004266.

We are an equal opportunities employer, actively supporting inclusivity and diversity.  As a Disability Confident organisation, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. We are proud to hold a prestigious Gold Athena SWAN award in recognition of our inclusive culture, commitment and good practices towards advancing of gender equality. We offer an exciting, stimulating, diverse research environment and actively promote a family friendly workplace. The Institute is also a member of Stonewall’s Diversity Champions programme.

The John Innes Centre is a registered charity (No. 223852) grant-aided by the Biotechnology and Biological Sciences Research Council.

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