A Postdoctoral Researcher position is available in the Professor Dame Caroline Dean Group to study antisense-mediated transcriptional regulation.
The Dean group studies mechanisms of RNA-mediated chromatin regulation using genetic, molecular, and most recently, structural analysis (with MRC, LMB Cambridge).
They investigate the sense-antisense circuitry at the Arabidopsis floral repressor locus FLC, how it links to alternative chromatin states that mediate transcriptional output and epigenetic switching, and how this has enabled adaptation to a range of habitats.
Working as part of a team led by Professor Caroline Dean, you will work on a research project dissecting how an RNA-binding protein (FCA), RNA 3’ processing factors and chromatin modifiers interact mechanistically to transcriptionally regulate FLC.
In this role, you will have the opportunity to interact closely with the Norwich team of ~ 10, all focused on FLC regulation, exploit a wealth of previously generated resources, and collaborate widely with other groups internationally.
The ideal candidate
You will have a PhD in Molecular Biology or similar.
You will have knowledge of transcriptional/chromatin control and/or non-coding RNA function, and demonstrable success in scientific writing and oral research presentations.
Interviews are expected to be held in early June by video-link.
Further information and details of how to apply can be found here, or contact the Human Resources team on 01603 450462 or firstname.lastname@example.org quoting reference 1003888.
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