Postdoctoral Researcher (Dean Group)

An exciting opportunity has arisen for a Postdoctoral Researcher to join the Dean Group at the John Innes Centre, working on cutting-edge science in the field of Cell and Developmental Biology.

About the Dean Group

The Dean group works on gene regulatory mechanisms linking co-transcriptional processing, transcription, and chromatin.

The lab’s activities currently focus on:

  • Quantitative variation in FLC expression – This influences whether a plant overwinters before flowering and is through an antisense-linked chromatin mechanism
  • Epigenetic switching – Plants remember they have experienced winter in a process called vernalization. This is an epigenetic silencing of FLC expression through a cis-based, Polycomb switching mechanism
  • Natural variation – Arabidopsis thaliana adaptation to different latitudes has involved noncoding polymorphisms within FLC that confer natural variation in flowering and vernalization response

The Postdoctoral Researchers in the lab work closely together to elucidate mechanisms whereby non-coding transcription impacts sense transcriptional output via epigenetic switches. We focus on one particular gene Arabidopsis FLC but work closely with collaborators to see if our findings are generic across the genome.

The role

The Postdoctoral Researcher will work on elucidating mechanisms whereby non-coding transcription impacts sense transcriptional output via epigenetic switches. The post holder will develop skills in co-transcriptional mechanisms that determine transcriptional outputs in many genomes. They will interact with scientists in the Dean lab, China and at LMB, Cambridge.

The Postdoctoral Researcher will read widely covering literature from many organisms and they will attend conferences and develop important networks for future collaborations.

The ideal candidate

They will have a PhD in Molecular Biology or in a related discipline with previous experience working with chromatin, transcription, and non-coding RNA analysis. Good communication and organisation skills with the ability to work independently are also required.

Additional information

Further information and details of how to apply can be found here, or contact the Human Resources team on 01603 450462 or quoting reference 1004322.

We are an equal opportunities employer, actively supporting inclusivity and diversity.  As a Disability Confident organisation, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy. We are proud to hold a prestigious Gold Athena SWAN award in recognition of our inclusive culture, commitment and good practices towards advancing of gender equality. We offer an exciting, stimulating, diverse research environment and actively promote a family friendly workplace. The Institute is also a member of Stonewall’s Diversity Champions programme.

The John Innes Centre is a registered charity (No. 223852) grant-aided by the Biotechnology and Biological Sciences Research Council.

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