Biophysical Analysis

At the John Innes Centre we have two biophysical analysis technologies, which can be used to identify and quantify the binding of different interaction;

  • Surface Plasmon Resonance - a versatile, label-free system for detailed studies of biomolecular interactions in real time
  • Isothermal Titration Calorimetry - the gold standard technique to probe biomolecular interactions in solution, it is a thermodynamic technique that directly measures the heat released or absorbed during a biomolecular binding event

Both Surface Plasmon Resonance and Isothermal Titration Calorimetry are available to all John Innes Centre and Norwich Research Park scientists, as well as in collaboration with scientists from other research facilities.

The team can all advise you on the best technique to use and help you to run your experiments.

Training on our biophysical analysis facilities

The biophysical analysis team run frequent training sessions on both Surface Plasmon Resonance and isothermal Titration Calorimetry.

The next training dates are;

  • Monday 2 July
  • Tuesday 2 October

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