Isothermal Titration Calorimetry is the gold standard technique to probe biomolecular interactions in solution and is a thermodynamic technique. It directly measures the heat released or absorbed during a biomolecular binding event.
In a single Isothermal Titration Calorimetry experiment, you can determine multiple binding parameters such as binding constants, stoichiometry, enthalpy and entropy. Providing a complete thermodynamic profile of a molecular interaction in a single experiment.
Our Isothermal Titration Calorimetry has a MicroCal PEAQ-ITC (Malvern), a highly sensitive, low volume isothermal titration calorimeter for the label-free in-solution study of biomolecular interactions.