Genome and Epigenome Regulation and Diversity

The ‘Genome and Epigenome Regulation and Diversity’ theme aims to understand how the diversity and regulation of genes in plants give rise to different physical traits for example, early flowering and salt responses.

We also aim to further our understanding of the consequences of disruptions such as whole genome duplication, environmental change, and domestication and how these have shaped plant genomes (the entire set of its genes).

The theme has two objectives;

Epigenetic Modification, Chromatin Structure and Gene Regulation (DeanFengHoward, Kumar, ØstergaardZilbermann)

We aim to understand the fundamental mechanisms underlying chromatin based gene regulation, investigate the role of H2A.Z nucleosomes in gene regulation and their interaction with developmental/environmental transcriptional regulators and elucidate the mechanisms and functions of DNA methylation.

Genome Maintenance, Diversity and Adaptive Evolution (Bevan, Bomblies, Coen and Yant)

This objective aims to understand adaptation in hybrid, non-hybrid and polyploid populations of Antirrhinum and Brassicaceae species and study the role that intra-genomic coevolution plays in complex adaptations. We will identify the genomic consequences of adaptation to challenging growing conditions and study the regulation of triploid and hexaploid genomes.