Sara Henderson

Postgraduate Researcher Molecules from Nature

DNA gyrase is currently used as a clinical antibiotic target against the quinolones such as ciprofloxacin.

However, clinical resistance is rising and the development of new antibiotics is not. Hence, Sara is interested in developing and further characterising DNA gyrase as a target for novel antibiotics acting through using a variety of biochemical and microbial techniques.

In particular Sara’s major interest lies within DNA gyrase from Mycobacterium tuberculosis the causative agent of TB.