Jake is a Postgraduate student in the Janneke Balk lab, studying Molecular Medicine MSc at the University of East Anglia.
The majority of the energy our bodies produce, in the form of ATP, is ‘manufactured’ via a process known as oxidative phosphorylation, which occurs in the mitochondria. This process occurs through the concerted action of 5 enzyme complexes. The first of these complexes is Complex I.
Jake is working on elucidating the role of the mitochondrial protein NUBPL (Nucleotide Binding Protein-Like) in complex I assembly.