Due to the emergence of antimicrobial resistance in disease-causing microbes, the range of antibiotics currently available for clinical use is declining.
This means there is an increasing need for new antibiotics. Soil-dwelling bacteria, such as Streptomyces, are reservoirs of antimicrobial agents just waiting to be discovered.
Corinne is currently characterising a new group of antimicrobials with the aim of identifying their mode of action.
She is also aiming to identify any mechanisms of resistance that can develop in disease-causing microbes and how easy or difficult it is for resistance to emerge.