Alistair Gibbons

Postgraduate Researcher

Microcin B17 (MccB17) inhibits DNA Gyrase in prokaryotes, however, its mechanism of action is not known.

Alistair is testing the activity of MccB17 on E. coli Gyrase mutants resistant to quinolone antibiotics.

If these mutants show resistance to MccB17, then the mechanism of MccB17 is likely to be similar to that of quinolones.