Dr Martin Trick
Computational and Systems Biology
My research is centred on the use of computational genomics for crop improvement by enabling predictive breeding for key desirable agronomic traits. Advances in sequencing technology have revolutionised the way in which this can be achieved. It is now feasible even in crop plants with very large and complex genomes such as wheat.
Much of the work I’m engaged in uses Illumina transcriptome sequencing in order to gather data on variation both in sequence and in expression of genes sampled across populations of genotypes or across diversity panels. Associative transcriptomics can then be used to seek significant correlations between SNP or expression markers and measured phenotypic traits. This methodology can be applied even to organisms lacking established genomics resources, as de novo transcriptome assembly can always be used to create a bespoke reference sequence. The strategy has been used successfully in oilseed rape, vegetable brassicas and bread wheat and is now being applied to identify markers in ash trees for tolerance of the Ash dieback disease.
ContactTel: 01603 450557
Plant Cell 29 p1864-1882
Publisher’s version: 10.1105/tpc.17.00389
Awake1, an ABC-Type Transporter, Reveals an Essential Role for Suberin in the Control of Seed Dormancy.
Plant Physiology 174 p276-283
Publisher’s version: 10.1104/pp.16.01556
Elucidation of the genetic basis of variation for stem strength characteristics in bread wheat by Associative Transcriptomics
BMC Genomics 17 p500
Publisher’s version: 10.1186/s12864-016-2775-2
The starch granule-associated protein EARLY STARVATION1 (ESV1) is required for the control of starch degradation in Arabidopsis thaliana leaves
Plant Cell 28 p1472-1489
Publisher’s version: doi:10.1105/tpc.16.00011
Nucleic Acids Research 44 p1-11
Publisher’s version: 10.1093/nar/gkw100
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