John Innes Centre site search

Faridoon K Yousafzai

Macromolecular Modelling and Dynamic Simulations

Arabidopsis thaliana is being used by the Dean Lab as a model system for analysing genes conferring a vernalization requirement and we are identifying and characterising genes that mediate a vernalization response

Selected Publications

Anne Edwards, Anne B. Heckmann, Faridoon Yousafzai, Gerard Duc and J. Allan Downie (2007) Structural implications of mutations in the pea SYM8 symbiosis gene, the DMI1 orthologue, encoding a predicted ion channel. Molecular Plant-Microbe Interactions (in Press)

Lisa M. Smith, Olga Pontes, Iain Searle, Nataliya Yelina, Faridoon K. Yousafzai, Alan J. Herr, Craig S. Pikaard, and David C. Baulcombe (2007) An SNF2 Protein Associated with Nuclear RNA Silencing and the Spread of a Silencing Signal between Cells in Arabidopsis. Plant Cell 19: 1507-1521

Yousafzai, F.K. and Eady, R.R. (2002) Dithionite reduction kinetics of the dissimilatory Cu-containing nitrite reductase of Alcalegenes xylosoxidans; the SO2.- radical binds to the substrate binding type 2 Cu site before the type 2 Cu is reduced. J. Biol. Chem. 277: 34067-34073.

Prudencio, M., Sawers, G., Fairhurst, S. A., Yousafzai, F. K. and Eady, R.R. (2002) Alcalagines xylosoxisans dissimilatory nitrite reductase:  Alanine Substitution of the Surface-Exposed Histidine 139 ligand of the Type 1 Copper center Prevents electron transfer to the Catalytic Center. Biochemistry 41: 3430–3438.

Yousafzai, F. K. and Eady, R. R.(1999) MgATP independent hydrogen evolution catalyzed by nitrogenase: an explanation for the missing electron(s) in the MgADP-AlF4- transition state complex. Biochem. J. 339: 511-515.

John Innes Centre