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The Dean Lab
Arabidopsis thaliana is being used by the Dean Lab as a model system for analysing genes conferring a vernalization requirement and we are identifying and characterising genes that mediate a vernalization response

Our Research

A central regulator in flowering and vernalization is FLC, which represses the floral transition. We are focusing on pathways that promote and repress FLC expression. It turns out that FLC regulation provides an excellent system in which to define conserved chromatin regulatory pathways. We aim to understand the molecular basis of these different pathways, how their interaction antagonistically regulates a common target and how this interaction changes throughout the life-cycle and during the evolution of different flowering variants.

Model integration of different pathways involved in FLC regulation More about FRIGIDA More aboout Vernalization More about antonomous pathway More about autonomous pathway

 

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John Innes Centre