Publications

De Lucia F, Crevillen P, Jones AM, Greb T, Dean C (2008) A PHD-Polycomb Repressive Complex 2 triggers the epigenetic silencing of FLC during vernalization.
Proc Natl Acad Sci U S A. 105(44):16831-6

Bäurle I, Dean C. (2008) Differential interactions of the autonomous pathway RRM proteins and chromatin regulators in the silencing of Arabidopsis targets. PLoS ONE. Jul 16;3(7):e2733

Pien S, Fleury D, Mylne JS, Crevillen P, Inzé D, Avramova Z, Dean C, Grossniklaus U. (2008) ARABIDOPSIS TRITHORAX1 dynamically regulates FLOWERING LOCUS C activation via histone 3 lysine 4 trimethylation. Plant Cell. 20(3):580-8.

Sheldon CC, Hills MJ, Lister C, Dean C, Dennis ES, Peacock WJ. (2008) Resetting of FLOWERING LOCUS C expression after epigenetic repression by vernalization. Proc Natl Acad Sci U S A. 105(6):2214-9

Liu, F., Quesada, V., Crevillen, P., Baürle, I., Swiezewski, S., Dean, C. (2007) The Arabidopsis RNA binding protein FCA requires a Lysine Specific Demethylase 1 homologue to down-regulate FLC. Molecular Cell 28:398-407.

Baürle, I., Smith L, Baulcombe, D.C. Dean, C. (2007) Widespread role for the flowering time regulators FCA and FPA in RNA-mediated chromatin silencing Science 318: 109-112

Swiezewski, S., Crevillen, P., Liu, F., Ecker, J., Jerzmanowski, A., Dean, C. (2007) Small RNA-mediated chromatin silencing directed to the 3’ region of the developmental regulator, FLC. Proc. Natl. Acad. Sci 27, 3633-8

Greb T, Mylne JS, Crevillen P, Geraldo N, An H, Gendall AR, Dean C. (2007) The PHD Finger Protein VRN5 Functions in the Epigenetic Silencing of Arabidopsis FLC. Curr Biol. 17, 73-8

Zhao K, Aranzana MJ, Kim S, Lister C, Shindo C, Tang C, Toomajian C, Zheng H, Dean C, Marjoram P, Nordborg M. (2007) An Arabidopsis Example of Association Mapping in Structured Samples. PLoS Genet Jan 19;3(1):e4

Marquardt S, Boss PK, Hadfield J, Dean C. (2006) Additional targets of the Arabidopsis autonomous pathway members, FCA and FY. J Exp Bot. 57(13):3379-86

Shindo C, Lister C, Crevillen P, Nordborg M, Dean C. (2006) Variation in the epigenetic silencing of FLC contributes to natural variation in Arabidopsis vernalization response. Genes Dev 20(22):3079-83

Baurle, I & Dean, C. (2006) The timing of developmental transitions in plants. Cell. 2006 May 19;125(4):655-64

Toomajian, C., Hu, T., Aranzana, MJ., Lister, C., Tang, C., Zheng, H., Calíbrese, P., Dean, C., Nordborg, M. (2006) A nonparametric test reveals selection for rapid flowering in the Arabidopsis genome. PLoS Biology 4 e137

Mylne, J., Barrett L, Tessadori F, Mesnage S, Johnson L, Bernatavichute Y, Jacobsen SE Fransz P and Dean, C (2006) LHP1, the Arabidopsis homologue of HETEROCHROMATIN PROTEIN1 is required for the epigenetic silencing of FLC. PNAS 103, 5012-7

Mylne J, Greb T, Lister, C & Dean C (2005) Epigenetic regulation in the control of flowering. Cold Spring Harb Symp Quant Biol. 2004;69:457-64.

Aranzana, M, Kim, S., Zhao, K., Bakker E., Horton M., Jakob K., Lister C., Molitor J., Shindo C., Tang C., Toomajian C., Traw B., Zheng H., Bergelson J., Dean C., Marjoram P., Nordborg M. (2005) Genome-wide association mapping in Arabidopsis thaliana identifies previously known genes responsible for variation in flowering time and pathogen resistance. PLoS Genetics 1:e60

Henderson, I., Liu, F., Drea, S., Simpson, G.G. and Dean, C (2005) An allelic series reveals essential roles for FY in plant development in addition to flowering-time control. Development 132, 3597-607

Shindo, C., Aranzana, M.J., Lister, C., Baxter, C., Nicholls, C., Nordborg, M., Dean, C. (2005) Role of FRIGIDA and FLOWERING LOCUS C in determining variation in flowering time in Arabidopsis accessions. Plant Physiol. 138, 1163-73

Winichayakul, S., Beswick, N.L., Dean, C. and Macknight, R.C. (2005) Components of the Arabidopsis autonomous floral promotion pathway, FCA and FY, are conserved in monocots. Functional Plant Biology 32, 345 - 355

Henderson, I., Dean, C. (2004) Control of Arabidopsis flowering: the chill before the bloom. Development 131, 3829-3838

Boss, P., Bastow, R. Mylne, J., Dean, C. (2004) Multiple pathways in the decision to flower: enabling, promoting and resetting. Plant Cell 16, S18-S31.

Bastow R, Mylne J. S., Lister C., Lippman Z., Martienssen R.A. & Dean C. (2004) Vernalization requires epigenetic silencing of FLC by histone methylation. Nature 427, 164-167.

Bastow, R. and Dean, C. (2003) Deciding when to flower. Science 302, 1695-1697. Murtas, G., Reeves, P.H., Fu, Y-F., Bancroft, I., Dean, C., Coupland, G. (2003) A Nuclear Protease Required for Flowering-Time Regulation in Arabidopsis Reduces the Abundance of SUMO Conjugates. Plant Cell 15, 2308-2319.

Henderson, I., Shindo, C., Dean, C. (2003) The need for winter in the switch to flowering. Ann Rev Genet 2003 37: 371-92

Simpson, G.G. Dijkwel, P.P., Quesada, V, Henderson, I and Dean, C. (2003) FY is an RNA 3’-end-processing factor that interacts with FCA to control the Arabidopsis floral transition. Cell 113, 777-787.

Quesada, V., Macknight, R., Dean, C. and Simpson, G. (2003) Autoregulation of FCA pre-mRNA processing controls flowering time. EMBO J. 22, 3142-3152.

Gazzani, S., Gendall, A.R., Lister, C. and Dean, C. (2003) Analysis of the molecular basis of flowering time variation in Arabidopsis accessions. Plant Physiol. 132, 1107-1114.

Muskett, P.R., Clissold, L., Marocco, A., Springer, P.S., Martienssen, R. and Dean, C. (2003) A resource of mapped Ds launch pads for targeted insertional mutagenesis in the Arabidopsis genome. Plant Physiol 132, 506-516.

Levy, Y.Y., Mesnage, S., Mylne, J.S., Gendall, A. and Dean, C. (2002) Multiple roles of Arabidopsis VRN1 in vernalization and flowering time control. Science 297, 243-246.

Macknight, R., Duroux, M., Laurie, R., Dijkwel, P., Simpson, G. and Dean, C. (2002) Functional significance of the alternative transcript processing of the Arabidopsis floral promoter, FCA. The Plant Cell 14, 877-888.

Simpson, G.G. and Dean, C (2002) Arabidopsis, the Rosetta stone of flowering time? Science 296, 285-289.

Gendall, A.R., Levy, Y.Y., Wilson, A. and Dean, C. (2001) The VERNALIZATION 2 gene mediates the epigenetic regulation of vernalization in Arabidopsis. Cell 107, 525-535

Yamanaka, T., Ohta, T., Takahashi, M. Meshi, T., Schmidt, R. Dean, C., Naito S. and Ishikawa, M. (2000) TOM1, an Arabidopsis gene required for efficient multiplication of a tobamovirus, encodes a putative transmembrane protein. Proc. Natl. Acad. Sci. USA 97, 10107-10112.

Johanson, U., West, J., Lister, C., Michaels, S., Amasino, R. and Dean, C. (2000) Molecular analysis of FRIGIDA, a major determinant of natural variation in Arabidopsis flowering time. Science 290, 344-347.

Chandler, J. Martinez-Zapater, J.M., Dean, C. (2000) Mutations causing defects in the biosynthesis and response to gibberellins, abscisic acid and phytochrome B do not inhibit vernalization in Arabidopsis fca-1. Planta 210, 677-682.

Fransz, P., Armstrong, S., de Jong, H., Parnell, L., van Drunen, C., Dean, C., Zabel, P., Bisseling, T. and Jones, G. (2000) Integrated cytogenetic map of chromosome arm 4S of A. thaliana: Structural organization of heterochromatic knob and centromere region. Cell 100, 367-376.

Cho, R.J., Mindrinos, M., Richards, D., Sapolsky, R., Anderson, M., Drenkard, E., Dewdney, J., Reuber, L., Stammers, M., Federspiel, N., Thoelogis, A., Yang, W-H., Hubbeell, E., Au, M., Chung, E., Laskkari, D., Lemieux, B., Dean, C., Lipshutz, R., Ausubel, F., Davis, R. and Oefner, P. (1999) Genome-wide mapping with biallelic markers in Arabidopsis thaliana. Nature Genetics 23, 203-207.

Bhatt, A.M., Lister, C., Page, T., Fransz, P., Findlay, K., Jones, G.H., Dickinson, H.G. and Dean, C. (1999) The DIF1 gene of Arabidopsis is required for meiotic chromosome segregation and belongs to the REC8/RAD21 cohesin gene family. Plant J. 19, 463-472.

Marrison, J.L., Rutherford, S.M., Robertson, E.J., Lister, C., Dean, C. and Leech, R.M. (1999) The distinctive roles of five different ARC genes in the chloroplast division process in Arabidopsis. Plant J. 18, 651-662.

Simpson, G., Gendall, T. and Dean, C. (1999) When to switch to flowering. Ann. Rev. Cell Dev. Biol. 15, 519-550.

Page, T., Macknight, R. Yang, C-H., Dean, C. (1999) Genetic interactions of the Arabidopsis flowering time gene FCA, with genes regulating floral initiation. Plant J. 17, 231-239.

Levy, Y. and Dean, C. (1998) The transition to flowering. Plant Cell 10, 1973-1989.

Meinke D., Cherry, M., Dean, C., Rounsley, S.D., Koornneef, M. (1998) Arabidopsis thaliana: A model plant for genome analysis. Science 282, 662-667.

Alonso-Blanco, C., Peeters, A.J.M., Koornneef, M., Lister, C., Dean, C., van den Bosch, N., Pot, J. and Kuiper, M.T.R. (1998) Development of an AFLP based linkage map of Ler, Col and Cvi Arabidopsis thaliana ecotypes and construction of a Ler/Cvi recombinant inbred population. The Plant J. 14, 259-271

Bhatt, A., Lister, C., Crawford, N. and Dean, C. (1998) The transposition of Tag1 elements is increased in transgenic Arabidopsis lines. The Plant Cell 10, 427-434.

Cavell, A., Lydiate, D., Parkin, I., Dean, C. and Trick, M. (1998) A 30cM segment of Arabidopsis thaliana chromosome 4 has six collinear homologues within the Brassica napus genome. Genome 41, 62-69

Bevan, M., Bancroft, I., Bent, E., Love., Goodman, H. Dean, C., et al (1998) Analysis of 1.9Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana. Nature 391, 485-488.

Levy Y.and Dean, C. (1998) Control of flowering time. Current Opinion in Plant Biology Vol 1, 49-54.

Rinehart, T.A., Dean, C. and Weil, C. (1997) Comparative analysis of non-random DNA double-strand break repair following Ac transposon excision in maize and Arabidopsis. The Plant J. 12, 1419-1427.

Brandes, A., Thompson, H., Dean, C. and Heslop-Harrison, J.S. (1997) Multiple repetitive DNA sequences in the paracentromeric regions of Arabidopsis thaliana L Chromosome Res. 5, 238-246.

Macknight, R., Bancroft, I., Page, T., Lister, C., Schmidt, R., Love, K., Westphal, L., Murphy, G., Sherson, S., Cobbett, C. and Dean, C. (1997) FCA, a gene controlling flowering time in Arabidopsis, encodes a protein containing RNA-binding domains. Cell 89, 737-745.

Parker, J., Coleman, M.J., Szabo, V., Frost, L.N., Schmidt, R., van der Biezen, E.A., Moores, T., Dean, C., Daniels, M.J., Jones, J.D.G. (1997) The Arabidopsis downy mildew resistance gene RPP5 shares similarity to the Toll and interleukin-1 receptors with N and L6. The Plant Cell 9, 879-894.

Schmidt, R., Love, K., West, J., Lenehan, Z, Dean, C. (1997) Description of 31 YAC contigs spanning the majority of Arabidopsis thaliana chromosome 5. The Plant J. 11, 563-572.

Dietrich, R.A., Richberg, M.H., Schmidt, R., Dean, C. and Dangl, J.L. (1997) A novel zinc finger protein is encoded by the Arabidopsis LSD1 gene and functions as a negative regulator of plant cell death. Cell 88, 685-694.

Jarvis, P., Belzile, F. and Dean C (1997) Inefficient and incorrect processing of the Ac transposase transcript in iae1 and wild-type Arabidopsis thaliana. The Plant J. 11, 921-931.

Jarvis, P., Belzile, F., Page T. and Dean C. (1997) Increased Ac excision (iae); Arabidopsis thaliana mutations affecting Ac transposition. The Plant J. 11, 907-919.

Liu Y-G, Mitsukawa N, Lister C, Dean, C Whittier R. (1996) Isolation and mapping of a new set of 129 RFLP markers in Arabidopsis thaliana using recombinant inbred lines. The Plant J. 6, 733-736.

Thompson, H., Schmidt, R. Brandes, A., Heslop-Harrison, J.S. and Dean, C. (1996) A novel repetitive sequence associated with the centromeric regions of Arabidopsis thaliana. Mol Gen. Genet. 253, 247-252.

Thompson, H., Schmidt, R. and Dean, C. (1996) Analysis of the occurrence and nature of repeated DNA in an 850kb region of Arabidopsis thaliana chromosome 4. Plant Mol. Biol. 32, 553-557.

Thompson, H., Schmidt, R. and Dean, C. (1996) Identification and distribution of seven classes of middle-repetitive DNA in the Arabidopsis thaliana genome. Nuc. Acid Res. 24, 3017-3022.

Chandler, J., Wilson, A. and Dean, C (1996) Arabidopsis mutants showing an altered response to vernalization. The Plant J. 10, 637-644.

Bhatt, A., Page, T., Lawson, E., Lister, C. and Dean, C. (1996) Use of Ac as an insertional mutagen in Arabidopsis. The Plant Journal 9, 935-945.

Schmidt, R., West, J., Cnops, G., Love, K., Balestrazzi, A., Dean, C. (1996) Detailed description of 4 YAC contigs representing 17Mb of chromosome 4 of Arabidopsis thaliana ecotype Columbia. The Plant Journal 9, 101-111.

Clarke, J.H., Mithen, R., Brown, J. K.M. and Dean, C. (1995) QTL analysis of flowering time in Arabidopsis thaliana. Mol. Gen. Genet. 248, 278-286

Sundaresan, V., Springer, P., Volpe, T., Haward, S., Jones, J., Dean, C. and Martienssen, R. (1995) Patterns of gene action in plant development revealed by enhancer trap and gene trap transposable elements. Genes and Dev. 9, 1797-1810.

Mithen, R., Clarke, J., Lister, C. and Dean, C. (1995) Genetics of aliphatic glucosinolates. III Side chain structure of aliphatic glucosinolates in Arabidopsis thaliana. Heredity 74, 210-215.

Jansen, R.C., van Ooijen, J W., Stam, P., Lister, C. and Dean, C. (1995) Genotype by environment interaction in genetic mapping of multiple quantitative trait loci. Theor. Appl. Genet. 91, 33-37.

Goodman, H., Ecker, J. and Dean, C. (1995) The genome of Arabidopsis thaliana. Proc. Natl. Acad. Sci. 92, 10831-10835.

Schmidt, R., West, J., Love, K., Lenehan, Z., Lister, C., Thompson, H., Bouchez, D. and Dean C. (1995) Physical map and organization of Arabidopsis thaliana chromosome 4. Science 270, 480-483.

Dean, C. and Schmidt, R. (1995) Plant genomes: a current molecular description. Ann. Rev. Plant Physiol. 46, 395-418.

Lawson, E., Scofield, S., Sjodin, C., Jones, J. and Dean, C. (1994) Modification of the 5' untranslated leader region of the maize Activator element leads to increased activity in Arabidopsis. Mol. Gen. Genet. 245, 608-615.

Scheres, B., Wolkenfelt, H., Willemsen, V., Terlouw, M., Lawson, E., Dean, C. and Weisbeek, P. (1994) Embryonic origin of the Arabidopsis primary root and root meristem initials. Development 120, 2475-2487.

Dolan, L., Duckett, C.M., Grierson, C., Linstead, P., Schneider, K., Lawson, E., Dean, C., Poethig, S. and Roberts, K. (1994) Clonal relationships and cell patterning in the root epidermis of Arabidopsis. Development 120, 2465-2474.

ÕKeefe, D., Tepperman, J., Dean, C., Leto, K., Erbes, D. and Odell, J. (1994) Plant expression of a bacterial P450 that catalyzes activation of a sulfonylurea pro-herbicide. Plant Physiol. 105, 473-482.

Chandler, J. and Dean, C. (1994) Factors influencing the vernalization response and flowering time of late flowering mutants of Arabidopsis thaliana. J.Exp. Bot. 45, 1279-1288.

Jarvis, P., Lister, C., Szabo, V. and Dean, C (1994) Integration of CAPS markers into the RFLP map generated using recombinant inbred lines of Arabidopsis thaliana. Plant Mol. Biol. 24, 685-687.

Magrath, R., Bano, F., Morgner, M., Parkin, I., Sharpe, A., Lister, C., Dean, C., Turner, J., Lydiate, D. and Mithen, R. (1994) Genetics of aliphatic glucosinilates. 1. Side chain elongation in Brassica napus and Arabidopsis thaliana. Heredity 72, 290-299.

Schmidt, R., Putterill, J., Cnops, G., West, J., Coupland, G., Dean, C. (1994) Analysis of clones carrying repeated DNA sequences in two YAC libraries of Arabidopsis thaliana DNA. The Plant Journal 5, 735-744.

Clarke, J. and Dean, C. (1994) Mapping FRI - a locus controlling flowering time and vernalization response in Arabidopsis thaliana. Mol. Gen. Genet. 242, 81-89.

Parker, J. Szabo, V. Staskawicz, B. Lister, C. Dean, C., Daniels, M. Jones J. (1993) Phenotypic characterization and molecular mapping of the Arabidopsis thaliana locus RPP5 determining resistance to Peronospora parasitica. The Plant Journal 4, 821-831

Lister, C. and Dean C. (1993) Recombinant inbred lines for mapping RFLP and phenotypic markers in Arabidopsis thaliana. The Plant Journal 4, 745-750.

Bancroft, I. Jones, J. and Dean, C. (1993) Heterologous transposon tagging of the DRL1 locus in Arabidopsis. The Plant Cell 5, 631-638.

Bancroft, I. and Dean, C. (1993) Transposition pattern of the maize element Ds in Arabidopsis thaliana. Genetics. 134. 1221-1229.

Bancroft, I. and Dean, C. (1993) Factors affecting the excision frequency of the maize transposable element Ds in Arabidopsis thaliana. Mol Gen Genet. 240, 65-72.

Tsay, Y-F., Frank, M., Page, T., Dean, C., Crawford, N. (1993) Identification of a mobile endogenous transposon in Arabidopsis thaliana. Science 260, 342-344.

Schmidt, R. and Dean, C. (1993) Towards construction of an overlapping YAC library of the Arabidopsis genome. BioEssays. 15, 63-69.

Bhatt A. and Dean, C. (1992) Development of tagging systems in plants using heterologous transposons. Curr, Opin. in Biotech. 3, 152-158.

Bancroft, I., Westphal L., Schmidt R. and Dean C. (1992) PFGE-resolved RFLP analysis of the DNA of Arabidopsis using probes as large as whole YACs. Nuc. Acid Res. 20, 6201-6207.

Schmidt R., Cnops G., Bancroft I. and Dean C. (1992) Construction of an overlapping YAC library of the Arabidopsis thaliana genome. Aust. J. Plant Physiol. 19, 341-351.

Bancroft I., Bhatt A., Sjodin C., Scofield S., Jones J. and Dean C. (1992) Development of an efficient two element transposon tagging system in Arabidopsis thaliana. Mol. Gen. Genet. 233, 449-461.

Dean C., Sjodin C., Page T., Jones J. and Lister C. (1992) Behaviour of the maize transposable element Ac in Arabidopsis thaliana. The Plant Journal 2, 69-81.

Hwang I., Kohchi T., Hauge B., Goodman H., Schmidt R., Cnops G., Dean C., Gibson S., Iba K.,Lemieux B.,Arondel V., Danhoff L. and Somerville C. (1991) Identification and map position of YAC clones comprising one third of the Arabidopsis genome. The Plant Journal, 1, 367-374.