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Sam MugfordSam Mugford

I am investigating the mechanisms of acylation of natural products in plants, focussing on the acylation of oat root triterpenoid glycosides in collaboration with Dr. Rebecca Goss’ laboratory (School of Chemical Science and Pharmacy, University of East Anglia).

I am also looking at the biological consequences of this process. In addition I am investigating the possible role of plant natural products in competitive interactions between plants.

The availability of the oat mutant collection in the Osbourn lab provides a unique opportunity to study allelopathy.

I am generally interested in exotic areas of plant metabolism, and have previously worked on alkaloid, and poly-unsaturated fatty acid metabolism; mineral nutrition and heavy-metal tolerance; and plant defence responses.

Funding

BBSRC grant no. BB/E009912/1.

 

Some acyl groups from biologically active plant triterpenoid glycosides

Some acyl groups from biologically active plant triterpenoid glycosides

Publications

Ingle RA, Mugford ST, Rees JD, et al.
Constitutively high expression of the histidine biosynthetic pathway contributes to nickel tolerance in hyperaccumulator plants
PLANT CELL 17 (7): 2089-2106 2005

Qi BX, Fraser T, Mugford S, et al.
Production of very long chain polyunsaturated omega-3 and omega-6 fatty acids in plants
NATURE BIOTECHNOLOGY 22 (6): 739-745 2004

Mugford ST, Mallon EB, Franks NR
The accuracy of Buffon's needle: a rule of thumb used by ants to estimate area
BEHAVIORAL ECOLOGY 12 (6): 655-658 2001