Eva Wegel

 I completed my PhD on cytogenetics of transgene expression in wheat with Professor Peter Shaw, Department of Cell and Developmental Biology, John Innes Centre. 

I joined the Osbourn lab in 2005 as a postdoctoral researcher on a collaborative project between the Osbourn and Shaw labs.  Here I am applying my experience of in situ hybridisation and other cytological methods to investigate the regulation of expression of clustered genes for the synthesis of defence-related compounds (avenacins) in oat. 

Funding

BBSRC grant BB/C504435/1.

Santos AP, Wegel E, Allen GC, Thompson WF, Stoger E, Shaw P, Abranches R, In situ methods to localize transgenes and transcripts in interphase nuclei: a tool for transgenic plant research, Plant Methods (2006), Nov 2; 2:18

Wegel E and Shaw P, Gene activation and deactivation related changes in the three-dimensional structure of chromatin, Chromosoma (2005) 114 (5), 331-7

Wegel E, Pilling E,  Calder G, Drea S, Doonan J, Dolan L, and Shaw P, Three-dimensional modelling of wheat endosperm development, New Phytologist (2005) 168 (1), 253-262

Wegel E, Vallejos RH, Christou P,  Stöger E and Shaw P, Large-scale chromatin decondensation induced in a developmentally activated transgene locus, Journal of Cell Science (2005), 118 (5), 1021-1031

Wegel E and Shaw P, Chromosome organisation in wheat endosperm and embryo, Cytogenetic and Genome Research (2005) 109(1-3), 331-337

Kohli A, Twyman RM, Abranches R, Wegel E, Stoger E and Christou P, Transgene integration, organization and interaction in plants, Plant Mol Biol (2003) 52(2): 247-258