John Innes Centre

Dr Stephen Bornemann

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Curriculum Vitae

  • 1983-1986 BSc Biochemistry, Kings College London
  • 1986-1987 MSc Applied Molecular Biology and Biotechnology, University College London
  • 1987-1989 Tate & Lyle Research and Technology
  • 1989-1992 PhD in Biological Chemistry with Prof David HG Crout, University of Warwick
  • 1993-1995 Post-doctoral Fellow, University of Sussex
  • 1996-present Project Leader, John Innes Centre
  • 2000-present Chartered Chemist and Member of the Royal Society of Chemistry
  • 2000-2006 Honorary Lecturer, School of Chemical Sciences and Pharmacy, University of East Anglia
  • 2005-present Associate Head of Biological Chemistry Department
  • 2005-present Chartered Scientist
  • 2006-20012 Honorary Senior Lecturer, School of Chemistry, University of East Anglia
  • 2012-present Honorary Senior Lecturer, School of Biological Sciences, University of East Anglia

Stephen Bornemann

Associate Head of Department

Biological Chemistry

Contact details

Tel: +44 (0)1603 450741
stephen.bornemann@jic.ac.uk

Research interests

Our current lines of enquiry include polyglucan and starch biosynthesis in plants and microbes, and symbiosis signalling in plants. We are a multidisciplinary group that studies enzymes at the atomic level using biochemical and biophysical methods along with complementary molecular biology approaches to address physiological function. Enzymes that have been studied previously include cupins, such as oxalate-degading enzymes, and chorismate synthase.

Selected Publications

Chandra G., Chater K. F., Bornemann S. (2011)
Unexpected and widespread connections between bacterial glycogen and trehalose metabolism.
Microbiology 157 (6) 1565-1572
DOI:10.1099/mic.0.044263-0
Syson K., Stevenson C. E. M., Rejzek M., Fairhurst S. A., Nair A., Bruton C. J., Field R. A., Chater K. F., Lawson D. M., Bornemann S. (2011)
Structure of a Streptomyces maltosyltransferase GlgE: a homologue of a genetically validated anti-tuberculosis target
Journal of Biological Chemistry 286 (44) 38298-38310
DOI:10.1074/jbc.M111.279315
Kalscheuer K., Syson K., Veeraraghavan U., Weinrick B., Biermann K. E., Liu Z., Sacchettini J. C., Besra G., Bornemann S., Jacobs W. R. (2010)
Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an alpha-glucan pathway
Nature Chemical Biology 6 (5) 376-384
DOI:10.1038/nchembio.340
Clé C., Gunning A. P., Syson K., Bowater L., Field R. A., Bornemann S. (2008)
Detection of transglucosidase-catalyzed polysaccharide synthesis on a surface in real time using surface plasmon resonance spectroscopy.
Journal of the American Chemical Society 130 (46) 15234-5
DOI:10.1021/ja805264w

Recent Publications

Clé C., Martin C., Field R. A., Kuzmic P., Bornemann S. (2010)
Detection of enzyme-catalyzed polysaccharide synthesis on surfaces
Biocatalysis and Biotransformation 28 (1) 64-71