Stanislav Kopriva

Project Leader

Metabolic Biology

Contact details

Tel: +44 (0)1603 450276
stanislav.kopriva@bbsrc.ac.uk

Research interests

My research focuses on understanding

molecular mechanisms of control of nutrient uptake and assimilation,
molecular basis of nutrient use efficiency,
variations in nutrient assimilation during evolution of higher plants.

To address these fundamental questions we use a combination of molecular, physiological, and biochemical methods and exploit natural genetic variation in the model plant A. thaliana. The program builds on my expertise in plant sulfur metabolism and expands to address more general questions of plant mineral nutrition.

Selected Publications

Davidian J. C., Kopriva S. (2010)
Regulation of sulfate uptake and assimilation - the same or not the same?
Molecular Plant 3 (2) 314-25
DOI:10.1093/mp/ssq001

Yatusevich R., Mugford S. G., Matthewman C., Gigolashvili T., Frerigmann H., Delaney S., Koprivova A., Flügge U. I., Kopriva S. (2010)
Genes of primary sulfate assimilation are part of the glucosinolate biosynthetic network in Arabidopsis thaliana.
Plant Journal 62 (1) 1-11
DOI:10.1111/j.1365-313X.2009.04118.x

Kopriva S., Mugford S. G., Matthewman C., Koprivova A. (2009)
Plant sulfate assimilation genes: redundancy versus specialization.
Plant Cell Reports 28 (12) 1769-80
DOI:10.1007/s00299-009-0793-0

Mugford S. G., Yoshimoto N., Reichelt M., Wirtz M., Hill L., Mugford S. T., Nakazato Y., Noji M., Takahashi H., Kramell R., Gigolashvili T., Flügge U. I., Wasternack C., Gershenzon J., Hell R., Saito K., Kopriva S. (2009)
Disruption of adenosine-5'-phosphosulfate kinase in Arabidopsis reduces levels of sulfated secondary metabolites
Plant Cell 21 (3) 910-927
DOI:10.1105/tpc.109.065581

Koprivova A., North K. A., Kopriva S. (2008)
Complex signaling network in regulation of sulfate assimilation by salt stress in Arabidopsis roots
Plant Physiology 146 (3) 1408-1420

Patron N., Durnford D., Kopriva S. (2008)
Sulfate assimilation in eukaryotes: evolutionary origins and subcellular localisation
BMC Evolutionary Biology 8 Article 39

Kopriva S., Fritzemeier K., Wiedemann G., Reski R. (2007)
The putative moss 3'phosphoadenosine 5'phosphosulfate reductase is a novel form of adenosine 5'phosphosulfate reductase without iron sulfur cluster
Journal of Biological Chemistry 282 22930-22938

Loudet O., Saliba-Colombani V., Camilleri C., Calenge F., Gaudon V., Koprivova A., North K.A., Kopriva S., Daniel-Vedele F. (2007)
Natural variation for sulfate content in Arabidopsis is highly controlled by adenosine 5'-phosphosulfate reductase
Nature Genetics 39 896-900

Kopriva S. (2006)
Regulation of sulfate assimilation in Arabidopsis and beyond
Annals of Botany 97 479-495

Recent Publications

Hermsen C., Koprivova A., Matthewman C., Wesenberg D., Krauss G. J., Kopriva S. (2010)
Regulation of sulfate assimilation in Physcomitrella patens: mosses are different!
Planta 232 (2) 461-70
DOI:10.1007/s00425-010-1190-1

Herschbach C., Rizzini L., Mult S., Hartmann T., Busch F., Peuke A. D., Kopriva S., Ensminger I. (2010)
Over-expression of bacterial gamma-glutamylcysteine synthetase (GSH1) in plastids affects photosynthesis, growth and sulphur metabolism in poplar (Populus tremula x Populus alba) dependent on the resulting gamma-glutamylcysteine and glutathione levels.
Plant, Cell and Environment 33 (7) 1138-51
DOI:10.1111/j.1365-3040.2010.02135.x

Mugford S. G., Matthewman C. A., Hill L., Kopriva S. (2010)
Adenosine-5'-phosphosulfate kinase is essential for Arabidopsis viability.
FEBS letters 584 (1) 119-23
DOI:10.1016/j.febslet.2009.11.014

Scheerer U., Haensch R., Mendel R. R., Kopriva S., Rennenberg H., Herschbach C. (2010)
Sulphur flux through the sulphate assimilation pathway is differently controlled by adenosine 5'-phosphosulphate reductase under stress and in transgenic poplar plants overexpressing gamma-ECS, SO, or APR.
Journal of Experimental Botany 61 (2) 609-22
DOI:10.1093/jxb/erp327

Wiedemann G., Hermsen C., Melzer M., Büttner-Mainik A., Rennenberg H., Reski R., Kopriva S. (2010)
Targeted knock-out of a gene encoding sulfite reductase in the moss Physcomitrella patens affects gametophytic and sporophytic development.
FEBS letters 584 (11) 2271-8
DOI:10.1016/j.febslet.2010.03.034

Hockin N., Malin G., Kopriva S. (2009)
Sulfur metabolism in marine phytoplankton: biochemical process to climate.
Sulfur Metabolism in Plants: Regulatory Aspects, Significance of Sulfur in the Food Chain, Agriculture and the Environment.
Backhuys, Leiden; Magraf, Weikersheim.
(Part III) 285-288

Kopriva S. (2009)
Sulfur assimilation in lower plants and algae: surprising lessons from sequenced genomes.
Sulfur Metabolism in Plants: Regulatory Aspects, Significance of Sulfur in the Food Chain, Agriculture and the Environment.
Backhuys, Leiden; Magraf, Weikersheim.
(Part III) 293-297

Koprivova A., Durenkamp M., Kopriva S. (2009)
Control of root growth by glutathione.
Sulfur Metabolism in Plants: Regulatory Aspects, Significance of Sulfur in the Food Chain, Agriculture and the Environment.
Backhuys, Leiden; Magraf, Weikersheim.
(Part III) 101-104.

Koralewska A., Buchner P., Stuiver C. E., Posthumus F. S., Kopriva S., Hawkesford M. J., De Kok L. J. (2009)
Expression and activity of sulfate transporters and APS reductase in curly kale in response to sulfate deprivation and re-supply.
Journal of Plant Physiology 166 (2) 168-79
DOI:10.1016/j.jplph.2008.03.005

Matthewman C., Mugford S. G., Kopriva S. (2009)
Bio-computational analysis of differential expression of individual ATP sulfurylase genes in Arabidopsis Thaliana
Sulfur Metabolism in Plants: Regulatory Aspects, Significance of Sulfur in the Food Chain, Agriculture and the Environment
Backhuys, Leiden; Magraf, Weikersheim
(Part III) 185-188

Mugford S. G., Reichelt M., Yoshimoto M., Nakazato Y., Noji M., Takahashi H., Saito K., Gershenzon J., Kopriva S. (2009)
Characterization of the APS kinase gene family in Arabidopsis thaliana.
Sulfur Metabolism in Plants: Regulatory Aspects, Significance of Sulfur in the Food Chain, Agriculture and the Environment
Backhuys, Leiden; Magraf, Weikersheim
(Part III) 189-193

North K. A., Ehlting B., Koprivova A., Rennenberg H., Kopriva S. (2009)
Natural variation in Arabidopsis adaptation to growth at low nitrogen conditions
Plant Physiology and Biochemistry 47 (10) 912-8
DOI:10.1016/j.plaphy.2009.06.009

Kopriva S., Patron N., Leustek T., Keeling P. (2008)
Phylogenetic analysis of sulfate assimilation and cysteine biosynthesis in phototrophic organisms
Advances in Photosynthesis and Respiration 27 33-60

Koprivova A., Kopriva S. (2008)
Lessons from investigation of regulation of APS reductase by salt stress.
Plant Signaling & Behavior 3 (8) 567-569

Koralewska A., Stuiver C. E. E., Posthumus F. S., Kopriva S., Hawkesford M. J., De Kok L. J. (2008)
Regulation of sulfate uptake, expression of the sulfate transporters Sultr1;1 and Sultr1;2, and APS reductase in Chinese cabbage (Brassica pekinensis) as affected by atmospheric H₂S nutrition and sulfate deprivation.
Functional Plant Biology 35 (4) 318-327
DOI:10.1071/FP07283

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