Stanislav Kopriva

Project Leader

Metabolic Biology

Contact details

Tel: +44 (0)1603 450276
stanislav.kopriva@jic.ac.uk

Research interests

My research focuses on understanding

molecular mechanisms of control of nutrient uptake and assimilation,
molecular basis of nutrient use efficiency,
variations in nutrient assimilation during evolution of higher plants.

To address these fundamental questions we use a combination of molecular, physiological, and biochemical methods and exploit natural genetic variation in the model plant A. thaliana. The program builds on my expertise in plant sulfur metabolism and expands to address more general questions of plant mineral nutrition.

Selected Publications

Kawashima C. G., Matthewman C. A., Huang S., Lee B. R., Yoshimoto N., Koprivova A., Rubio-Somoza I., Todesco M., Rathjen T., Saito K., Takahashi H., Dalmay T., Kopriva S. (2011)
Interplay of SLIM1 and miR395 in the regulation of sulfate assimilation in Arabidopsis.
Plant Journal 66 (5) 863-876
DOI:10.1111/j.1365-313X.2011.04547.x

Lee B. R., Koprivova A., Kopriva S. (2011)
The key enzyme of sulfate assimilation, adenosine 5'-phosphosulfate reductase, is regulated by HY5 in Arabidopsis
Plant Journal 67 (6) 1042-54
DOI:10.1111/j.1365-313X.2011.04656.x

Takahashi H., Kopriva S., Giordano M., Saito K., Hell R. (2011)
Sulfur assimilation in photosynthetic organisms: molecular functions and regulations of transporters and assimilatory enzymes.
Annual Review of Plant Biology 62 157-84
DOI:10.1146/annurev-arplant-042110-103921

Davidian J. C., Kopriva S. (2010)
Regulation of sulfate uptake and assimilation - the same or not the same?
Molecular Plant 3 (2) 314-25
DOI:10.1093/mp/ssq001

Yatusevich R., Mugford S. G., Matthewman C., Gigolashvili T., Frerigmann H., Delaney S., Koprivova A., Flügge U. I., Kopriva S. (2010)
Genes of primary sulfate assimilation are part of the glucosinolate biosynthetic network in Arabidopsis thaliana.
Plant Journal 62 (1) 1-11
DOI:10.1111/j.1365-313X.2009.04118.x

Kopriva S., Mugford S. G., Matthewman C., Koprivova A. (2009)
Plant sulfate assimilation genes: redundancy versus specialization.
Plant Cell Reports 28 (12) 1769-80
DOI:10.1007/s00299-009-0793-0

Mugford S. G., Yoshimoto N., Reichelt M., Wirtz M., Hill L., Mugford S. T., Nakazato Y., Noji M., Takahashi H., Kramell R., Gigolashvili T., Flügge U. I., Wasternack C., Gershenzon J., Hell R., Saito K., Kopriva S. (2009)
Disruption of adenosine-5'-phosphosulfate kinase in Arabidopsis reduces levels of sulfated secondary metabolites
Plant Cell 21 (3) 910-927
DOI:10.1105/tpc.109.065581

Koprivova A., North K. A., Kopriva S. (2008)
Complex signaling network in regulation of sulfate assimilation by salt stress in Arabidopsis roots
Plant Physiology 146 (3) 1408-1420

Patron N., Durnford D., Kopriva S. (2008)
Sulfate assimilation in eukaryotes: evolutionary origins and subcellular localisation
BMC Evolutionary Biology 8 Article 39

Kopriva S., Fritzemeier K., Wiedemann G., Reski R. (2007)
The putative moss 3'phosphoadenosine 5'phosphosulfate reductase is a novel form of adenosine 5'phosphosulfate reductase without iron sulfur cluster
Journal of Biological Chemistry 282 22930-22938

Loudet O., Saliba-Colombani V., Camilleri C., Calenge F., Gaudon V., Koprivova A., North K.A., Kopriva S., Daniel-Vedele F. (2007)
Natural variation for sulfate content in Arabidopsis is highly controlled by adenosine 5'-phosphosulfate reductase
Nature Genetics 39 896-900

Kopriva S. (2006)
Regulation of sulfate assimilation in Arabidopsis and beyond
Annals of Botany 97 479-495

Recent Publications

Hockin N. L., Mock T., Mulholland F., Kopriva S., Malin G. (2012)
The response of diatom central carbon metabolism to nitrogen starvation is different to that of green algae and higher plants
Plant Physiology 158 (1) 299-312
DOI:10.1104/pp.111.184333

Kopriva S. (2011)
Nitrogen and sulfur metabolism in C₄ plants
Advances in Photosynthesis and Respiration: C4 Photosynthesis and Related CO₂Concentrating Mechanisms
Springer
32 (7) 109-128
DOI:10.1007/978-90-481-9407-0

Mugford S. G., Lee B. R., Koprivova A., Matthewman C., Kopriva S. (2011)
Control of sulfur partitioning between primary and secondary metabolism.
Plant Journal 65 (1) 96-105
DOI:10.1111/j.1365-313X.2010.04410.x

Hermsen C., Koprivova A., Matthewman C., Wesenberg D., Krauss G. J., Kopriva S. (2010)
Regulation of sulfate assimilation in Physcomitrella patens: mosses are different!
Planta 232 (2) 461-70
DOI:10.1007/s00425-010-1190-1

Herschbach C., Rizzini L., Mult S., Hartmann T., Busch F., Peuke A. D., Kopriva S., Ensminger I. (2010)
Over-expression of bacterial gamma-glutamylcysteine synthetase (GSH1) in plastids affects photosynthesis, growth and sulphur metabolism in poplar (Populus tremula x Populus alba) dependent on the resulting gamma-glutamylcysteine and glutathione levels.
Plant, Cell and Environment 33 (7) 1138-51
DOI:10.1111/j.1365-3040.2010.02135.x

Koprivova A., des Francs-Small C. C., Calder G., Mugford S. T., Tanz S., Lee B. R., Zechmann B., Small I., Kopriva S. (2010)
Identification of a pentatricopeptide repeat protein implicated in splicing of intron 1 of mitochondrial nad7 transcripts.
Journal of Biological Chemistry 285 (42) 32192-9
DOI:10.1074/jbc.M110.147603

Koprivova A., Mugford S. T., Kopriva S. (2010)
Arabidopsis root growth dependence on glutathione is linked to auxin transport.
Plant Cell Reports 29 (10) 1157-1167
DOI:10.1007/s00299-010-0902-0

Mugford S. G., Matthewman C. A., Hill L., Kopriva S. (2010)
Adenosine-5'-phosphosulfate kinase is essential for Arabidopsis viability.
FEBS letters 584 (1) 119-23
DOI:10.1016/j.febslet.2009.11.014

Scheerer U., Haensch R., Mendel R. R., Kopriva S., Rennenberg H., Herschbach C. (2010)
Sulphur flux through the sulphate assimilation pathway is differently controlled by adenosine 5'-phosphosulphate reductase under stress and in transgenic poplar plants overexpressing gamma-ECS, SO, or APR.
Journal of Experimental Botany 61 (2) 609-22
DOI:10.1093/jxb/erp327

Wiedemann G., Hermsen C., Melzer M., Büttner-Mainik A., Rennenberg H., Reski R., Kopriva S. (2010)
Targeted knock-out of a gene encoding sulfite reductase in the moss Physcomitrella patens affects gametophytic and sporophytic development.
FEBS letters 584 (11) 2271-8
DOI:10.1016/j.febslet.2010.03.034

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