John Innes Centre

Prof Dale Sanders

Lab Pages

Lab MembersExpand lab members list

Related links

Curriculum Vitae

  • 1971-1974 B.A., Biology, University of York
  • 1975-1978 Ph.D., University of Cambridge (Botany School)
  • 1978-1983 Post-Doctoral Research Fellow, then Associate, Dept Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA
  • 1983-1989 Lecturer, Biology Department, University of York
  • 1989-1992 Reader, Biology Department, University of York
  • 1992- 2010 Professor, Biology Department, University of York
  • 2004-2010 Head of Department, Biology Department, University of York
  • 2010-present Director of John Innes Centre, Norwich

Dale Sanders


Metabolic Biology

Contact details

Research interests

Professor Dale Sanders’ research studies how plant cells respond to changes in their environment and how they store the nutrients they acquire. He is a leading authority on the mechanisms for the transport of chemical elements across cell membranes in plants. These mechanisms have key roles in the control of crucial crop traits such as nutritional value of foods, seed germination, the response to drought conditions and how plants cope with toxic compounds in the soil. Work in his laboratory on the characterisation of novel cation diffusion facilitators in Arabidopsis and cereals involved in the transport of zinc is identifying a bio-fortification strategy to enrich the endosperm in this heavy metal. Zinc deficiency is thought to impact on 30% of the world’s population, due in part, to the near absence of the metal in cereal endosperm.   Prof Sanders also works on the fundamental science of the specialised plant transport mechanisms involved in signalling which have important, but poorly understood roles in plant biology.  Professor Sanders has authored over 140 scientific papers, many of which have been highly cited and in 2001 was elected a Fellow of the Royal Society and awarded the European Science Prize of the Körber Foundation.


Selected Publications

Palmgren M. G., Clemens S., Williams L. E., Kraemer U., Borg S., Schjorring J. K., Sanders D. (2008)
Zinc biofortification of cereals: problems and solutions
Trends in Plant Science 13 464-473
Uelker B., Peiter E., Dixon D. P., Moffat C., Capper R., Bouche N., Edwards R., Sanders D., Knight H., Knight M. R. (2008)
Getting the most out of publicly available T-DNA insertion lines
Plant Journal 56 665-677
Whiteman S. A., Nuhse T. S., Ashford D. A., Sanders D., Maathuis F. J. M. (2008)
A proteomic and phosphoproteomic analysis of Oryza sativa plasma membrane and vacuolar membrane
Plant Journal 56 146-156
Whiteman S. A., Serazetdinova L., Jones A. M. E., Sanders D., Rathjen J., Peck S. C., Maathuis F. J. M. (2008)
Identification of novel proteins and phosphorylation sites in a tonoplast enriched membrane fraction of Arabidopsis thaliana
Proteomics 8 3536-3547
Dodd A. N., Gardner M. J., Hotta C. T., Hubbard K. E., Dalchau N., Love J., Assie J. M., Robertson F. C., Jakobsen M. K., Goncalves J., Sanders D., Webb A. A. R. (2007)
The Arabidopsis circadian clock incorporates a cADPR-based feedback loop
Science 318 1789-1792
Montanini B., Blaudez D., Jeandroz S., Sanders D., Chalot M. (2007)
Phylogenetic and functional analysis of the cation diffusion facilitator family: improved signature and prediction of substrate specificity
BMC Genomics 8 Art: 107
Peiter E., Montanini B., Gobert A., Pedas P., Husted S., Maathuis F. J. M., Blaudez D., Chalot M., Sanders D. (2007)
A secretory pathway-localised cation diffusion facilitator confers plant manganese tolerance
Proceedings of the National Academy of Sciences of the United States of America 104 8532-8537
Zancani M., Skiera L. A., Sanders D. (2007)
Roles of basic residues and salt-bridge interaction in a vacuolar H+-pumping pyrophosphatase (AVP1) from Arabidopsis thaliana
Biochimica et Biophysica Acta 1768 311-316

Recent Publications

Borrill P., Connorton J., Balk J., Miller T., Sanders D., Uauy C. (2014)
Biofortification of wheat grain with iron and zinc: integrating novel genomic resources and knowledge from model crops
Frontiers in Plant Science 5 (53)
Schroeder J. I., Delhaize E., Frommer W. B., Guerinot M. L., Harrison M. J., Herrera-Estrella L., Horie T., Kochian L. V., Munns R., Nishizawa N. K., Tsay Y. F., Sanders D. (2013)
Using membrane transporters to improve crops for sustainable food production.
Nature 497 (7447) 60-6
Podar D., Scherer J., Noordally Z., Herzyk P., Nies D., Sanders D. (2012)
Metal selectivity determinants in a family of transition metal transporters.
Journal of Biological Chemistry 287 (5) 3185-96