Claire Domoney
Project Leader
Metabolic Biology
Contact details
Tel: +44 (0)1603 450381
claire.domoney@bbsrc.ac.uk
Research interests
The focus of the laboratory is on understanding genetic and biochemical control of legume seed quality and nitrogen accumulation that is applicable to the development of improved crops for sustainable agriculture. Metabolite analysis is being used to identify the pleiotropic effects of mutations in protease inhibitors and other 'antinutritional' proteins, for which functions have not been defined. Variation in genes encoding enzymes of senescence-related processes is being studied for its significance to nitrogen reassimilation, and relevance to crop end use. Dissecting the function of individual genes is based on natural variation and TILLING mutant isolation. The lab is also investigating the link between plant stress and the profile of metabolites, to provide information on the effect of drought-stress on the metabolome.
Recent Publications
Charlton A. J., Donarski J. A., Harrison M., Jones S. A., Godward J., Oehlschlager S., Arques J. L., Ambrose M., Chinoy C., Mullineaux P. M., Domoney C. (2008)
Responses of the pea (Pisum sativum L.) leaf metabolome to drought stress assessed by nuclear magnetic resonance spectroscopyMetabolomics
4 (4) 312-327
DOI: 10.1007/s11306-008-0128-0