John Innes Centre

Dr Claire Domoney

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Curriculum Vitae

  • 1976 BSc, University College, Dublin
  • 1977 Higher Diploma in Education, University College, Dublin
  • 1978 MSc, University College, Dublin
  • 1982 PhD, University of East Anglia
  • 1982 Post-doctoral fellow, John Innes Centre
  • 1997 Project Leader, Department of Applied Genetics, John Innes Centre
  • 2001 Project Leader, Department of Metabolic Biology, John Innes Centre

Claire Domoney

Project Leader

Metabolic Biology

Contact details

Tel: +44 (0)1603 450381
claire.domoney@bbsrc.ac.uk

Research interests

The focus of the laboratory is on understanding genetic and biochemical control of legume seed quality and nitrogen accumulation that is applicable to the development of improved crops for sustainable agriculture. Metabolite analysis is being used to identify the pleiotropic effects of mutations in protease inhibitors and other 'antinutritional' proteins, for which functions have not been defined. Variation in genes encoding enzymes of senescence-related processes is being studied for its significance to nitrogen reassimilation, and relevance to crop end use. Dissecting the function of individual genes is based on natural variation and TILLING mutant isolation.  The lab is also investigating the link between plant stress and the profile of metabolites, to provide information on the effect of drought-stress on the metabolome.

Recent Publications

Charlton A. J., Donarski J. A., Harrison M., Jones S. A., Godward J., Oehlschlager S., Arques J. L., Ambrose M., Chinoy C., Mullineaux P. M., Domoney C. (2008)
Responses of the pea (Pisum sativum L.) leaf metabolome to drought stress assessed by nuclear magnetic resonance spectroscopy
Metabolomics 4 (4) 312-327
DOI: 10.1007/s11306-008-0128-0
Vigeolas H., Chinoy C., Zuther E., Blessington B., Geigenberger P., Domoney C. (2008)
Combined metabolomic and genetic approaches reveal a link between the polyamine pathway and albumin 2 in developing pea seeds.
Plant Physiology 146 (1) 74-82
DOI:10.1104/pp.107.111369