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John Innes Centre

Growth and Morphogenesis

Project Leaders:

Robert Sablowski
Mike Bevan
Enrico Coen

Work in the area of Growth and Morphogenesis addresses a fundamental question in biology: how the activities of individual cells contribute to the formation of tissues, organs and organisms.

image
Ectopic shoot tissue forming on roots of an Arabidopsis seedling mis-expressing the WUSCHEL gene, which maintains pluripotency in the meristem.

A good deal is known about genes involved in establishing regional identities, but little is known about how the actions of these genes leads to tissue and organ formation.

The objectives of our work are to understand how meristematic cells are maintained and their fates determined, and to define mechanisms regulating the differentiation of cells from their precursors, how plant architecture is determined by the meristem, and how growth regulators such as gibberellins and sugars contribute to organ formation and growth. The dynamics of growth are being captured and modelled to establish a quantitative framework for understanding gene function.